Richard Mendel MD, a Spinal Neurosurgeon from Tampa, Florida, gives a presentaion on the Basics of Stem Cells. Stem Cell Treatments are becoming more popular, and it benefit all to know the basics of this growing science.
Digital – a word which is ubiquitous within our industry now and no longer the exclusive domain of IT or marketing. It should not be seen as simply an enabler; intelligent and progressive digitisation is now a fundamental business need in all areas of pharma and healthcare.
We present an exclusive webinar with global data centre and interconnectivity specialist Equinix, joined by digital and technology experts FFW and moderated by our own Paul Tunnah. This debate will provide practical insight and delve deep into the challenges at hand in managing the digitisation of our industry.
Topics covered will include:
•Why being digital is no longer an IT function but rather a business need – analysis and insight into the current market and the coming 3 to 5 years
•Managing data – how pharma needs to change its IT foundations to remain commercially optimised in a changing healthcare environment, including the move from pill to patient
•How industry can prepare – why connected is not enough – definition and benefits of interconnectivity, with learnings from the financial sector
Chemical probes are powerful reagents with increasing impacts on biomedical research. However, probes of poor quality or that are used incorrectly generate misleading results. To help address these shortcomings, we are building a community-driven online resource to improve quality and convey current best practice.
In this presentation, we will highlight some selected examples of promising, high quality chemical probes and probes of lesser value. We will discuss the prevalence of using lesser quality probes and the costs. We will then detail our plans to develop the Chemical Probes Portal, a web-based resource annotated by the chemical biology community that allows users to reference the most appropriate chemical probe (or probes) for a given protein target. The Portal will be an online community of scientists, reviewers, editors.
This 30 minute webinar will describe the design and application of pooled CRISPR libraries. A Sigma-Aldrich technology expert will discuss unique features of Sigma CRISPR pooled libraries with special attention to CRISPR design and cell culture needs.
Enabling Reliable Compound Identification using LC-MSn
Reliable compound identification with non-targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a major challenge. It involves matching against reference data. For fast and automated identification, tandem mass spectral libraries are queried with appropriate search tools. Reliability of search as well as time and efforts spent for data reviewing very much depend on the quality of the database involved. In this presentation, we will give an overview on our efforts towards the development of a reliable, robust, and transferable tandem mass spectral database, and how such a database can successfully be implemented in workflows for comprehensive drug analysis.
Findings from the Veeva 2015 European Life Sciences Survey
Is the industry getting what it needs?
Customer data challenges are among the most vexing and pervasive that life sciences companies currently experience, especially with the increasing regulatory pressure and the transition to new business models they face. But are organisations getting what they need from their data to deliver true customer insight and drive commercial success?
If you are responsible for acquiring, maintaining or using commercial customer data and if better customer insight is important to you, this is your opportunity to hear more from the Veeva 2015 European Life Sciences Survey and participate in an interactive live online debate.
Hear from lead speakers Margit Marton, lead data owner, European business operations, Biogen, and Guillaume Roussel, director of strategy for Veeva OpenData, Veeva Systems, on
• How your organisation compares with the current market
• The challenges in sourcing and maintaining customer data
• New approaches to improve data quality, accessibility and compliance
• How customer data can be better employed for commercial success
Breast cancer is the most commonly diagnosed cancer in women, and is the second leading cause of death in women. Each year, over 220,000 women (as well as over 2000 men) are diagnosed with breast cancer, and over 40,000 succumb each year to the illness. With constant advancement of treatment options, the importance of accurate diagnosis and detection of breast cancer becomes more and more relevant to the survival of the patient. Immunohistochemistry has served as the catalyst for these advancements in breast cancer diagnosis. This presentation covers many of the basic science, facts, and statistics of breast cancer, as well as the utility of immunohistochemical testing with markers such as e-cadherin, p120 catenin, mammaglobin, and GATA3 in the accurate diagnosis and survival rates of breast cancer.
Poly(2-oxazoline) (POx) is a very promising candidate for use in polymer therapeutics. Amphiphilic POx triblock copolymers can be used as high capacity drug delivery systems for hydrophobic drugs, like paclitaxel, and exhibit synergistic effects for the delivery of multiple chemotherapeutics. In this talk, Professor Jordan will highlight the unparalleled high drug-loading capacities of POx systems, the polymer structural variability, and outline the consequences of the drug loading on the drug delivery system morphology.
Join West Pharmaceutical Services, Inc.'s Chris Evans and HealthPrize Technologies' Katrina Firlik to learn about how their organizations are collaborating to provide an end-to-end connected health solution that tracks, educates, motivates and engages patients to increase adherence and medical literacy and rewards them for compliance with their prescribed regimen.
Doping control analysis predominantly utilises chromatography and mass spectrometry-based approaches to detect prohibited substances and methods of doping. These compounds and methods present both low and high molecular weight analytes of xenobiotic or natural / endogenous origin, which are to be detected, and occasionally quantified, using state-of-the-art instruments.
The majority of the employed tools provides low resolving power. However, high resolution / high accuracy mass spectrometry has gained much attention recently due to: constantly increasing analytical requirements concerning the number of target compounds; the complexity of analytes (e.g. peptides and proteins); and the desire to accelerate analyses and obtain information (allowing for retrospective data mining).
A selection of compounds, new challenges, and methods currently employed in doping control laboratories will be presented to the audience including, for example: new anabolic agents referred to as selective androgen receptor modulators (SARMs); insulins; so-called "releasing peptides" that stimulate the endogenous production of natural hormones; and ways of manipulating drug tests.
Sample preparation is the most important, yet often most neglected area of chromatographic training and method development. The world's finest gas and liquid chromatographs generally cannot overcome mistakes made prior to sample injection.
This webinar will focus on general principles of sampling and sample preparation for chromatography and an overview of key concepts for several major sample preparation techniques, including:
* Liquid-liquid and liquid-solid extractions (LLE and LSE)
* Static headspace extraction (SHE)
* Solid phase extraction (SPE)
* Sorptive micro-extractions (SPME and SBSE).
Discussion will directed toward seeing the commonalities among all extraction techniques and toward choosing the best technique for a given analytical problem. Fundamentals of sample and glassware handling will also be reviewed.
This webinar is directed toward analysts who use these techniques hands-on every day and to the laboratory managers who must teach, train and supervise them.
In this webinar, Professor Peter Schoenmakers will provide insight into the various LC techniques, including:
* An overall perspective of current usage and applications of the various techniques.
* A description of how the techniques developed, starting from paper chromatography up-to current "high tech" two-dimensional separations.
* A more detailed focus on the concept of various methods.
Often portrayed more as magic than science, popular television series such as CSI have aroused great interest in analytical chemistry. Forensic science relies on separation science.
Peter Schoenmakers' webinar will also, in a light-hearted manner, put LC methods into the correct perspective for forensic science.
The first activity in the Year of Education is a series of free educational webinars, run in conjunction by separationsNOW and Chromedia. In the first webinar, Professor Harold McNair gives an interactive lecture on the basics of gas chromatography.
This first webinar is intended for persons who:
* Use chromatography and would like to revisit the basics of GC.
* Have a little knowledge and would like to learn more!
Some knowledge of general and organic chemistry is assumed. The webinar should prove useful to technicians, students, graduate students, PhDs and even professors planning to work with GC.
Topics to be discussed are:
* Definitions of GC
* Separation principles
* Advantages and limitations of GC
* Basic instrumental components of a GC
* Capillary columns
* Three detectors: FID,TCD and ECD
brought to you by separationsNOW.com (Wiley-Blackwell) and Chromedia
The Year of Education came about through discussions between 3 professors who actively teach chromatography:
* Professor Harold McNair, Virginia Tech, Blacksburg, USA
* Professor Pat Sandra, University of Ghent, Belgium
* Professor Peter Schoenmakers, University of Amsterdam, Netherlands
"The first activity is a free webinar on gas chromatography, followed by a number of other activities, more webinars, online short courses, tutorials, instruction videos and much more! 2010 will be a year full of activities.
Many experts will be involved, from university and industry. We believe all chromatographers should actively take part in this: in teaching, telling their employees and students to take courses. This is a chance they should not miss!"