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Medical Research

  • Need to judge your product? Use HPTLC to get insights into sample composition-S2
    Need to judge your product? Use HPTLC to get insights into sample composition-S2 Melanie Broszat, PhD CAMAG, Muttenz, Switzerland & Michaela Oberle Merck KGaA, Darmstadt, Germany Live 75 mins
    Thin-Layer Chromatography has been a well-known method for analysis of botanicals and other complex samples since the end of the 1930s. Today’s modern thin-layer chromatography combines the advantage of analytical robustness and high sample throughput with the possibility to use all kind of specific detection methods, e.g. classical UV/Vis/Fluorescence detection, mass spectrometry or effect-directed analysis. This method increases the amount of information for a fast and efficient screening for new compounds and the identification of raw materials especially for samples with a high matrix load such as herbal drugs, cosmetic and food samples.
    HPTLC, the most advanced form of Thin-Layer Chromatography, is a powerful yet simple and cost effective tool for testing identity, purity, and strength (content) of botanicals as well as excluding adulteration during quality control. With the publication of general chapters by the United States Pharmacopoeia (USP ) and European Pharmacopoeia (Ph.Eur. 2.8.25) HPTLC has officially come into existence as a highly standardized and therefore reproducible analytical technique. The use of high performance plates, suitable instrument and software, a standardized methodology, and validated methods ensures reliable results that are fully compliant with current Good Manufacturing Practice (cGMP). HPTLC fingerprints allow convenient visual comparison of multiple samples even if those originate from different plates (and different laboratories worldwide). Reference images (HPTLC fingerprints of botanical reference materials or other references) can be used to qualify data and pass/fail samples based on similarity or difference.
    We will give you an overview about the versatility of HPTLC, applicable to many of your analytical tasks. Don’t miss the chance to extend your knowledge!
  • Need to judge your product? Use HPTLC to get insights into sample composition
    Need to judge your product? Use HPTLC to get insights into sample composition Melanie Broszat, PhD CAMAG, Muttenz, Switzerland & Michaela Oberle Merck KGaA, Darmstadt, Germany Recorded: Feb 20 2018 52 mins
    Thin-Layer Chromatography has been a well-known method for analysis of botanicals and other complex samples since the end of the 1930s. Today’s modern thin-layer chromatography combines the advantage of analytical robustness and high sample throughput with the possibility to use all kind of specific detection methods, e.g. classical UV/Vis/Fluorescence detection, mass spectrometry or effect-directed analysis. This method increases the amount of information for a fast and efficient screening for new compounds and the identification of raw materials especially for samples with a high matrix load such as herbal drugs, cosmetic and food samples.
    HPTLC, the most advanced form of Thin-Layer Chromatography, is a powerful yet simple and cost effective tool for testing identity, purity, and strength (content) of botanicals as well as excluding adulteration during quality control. With the publication of general chapters by the United States Pharmacopoeia (USP ) and European Pharmacopoeia (Ph.Eur. 2.8.25) HPTLC has officially come into existence as a highly standardized and therefore reproducible analytical technique. The use of high performance plates, suitable instrument and software, a standardized methodology, and validated methods ensures reliable results that are fully compliant with current Good Manufacturing Practice (cGMP). HPTLC fingerprints allow convenient visual comparison of multiple samples even if those originate from different plates (and different laboratories worldwide). Reference images (HPTLC fingerprints of botanical reference materials or other references) can be used to qualify data and pass/fail samples based on similarity or difference.
    We will give you an overview about the versatility of HPTLC, applicable to many of your analytical tasks. Don’t miss the chance to extend your knowledge!
  • Get Published: Your How to Guide - Latin America
    Get Published: Your How to Guide - Latin America Dr. Gwen Taylor, Peter Creaton, Brian Collins and Eduardo Martinez Recorded: Feb 15 2018 56 mins
    Join us for the first webinar in the Wiley Learn to Publish series and learn all you need to know to publish your next article with confidence. Learn from and interact with top editors in the research community during the live Q&A sessions.

    Register for the first FREE webinar now and you will receive guidance from expert editors on:

    • Selecting the RIGHT journal – How to choose the best outlet for your research
    • Preparing your article – How to follow author guidelines
    • Creating a title and abstract - How to communicate your research effectively

    Future webinars will include 'Peer Review and Publishing Ethics - the dos and don'ts' and 'Sharing and Promoting your Research - SEO and Altmetrics'.

    Attend all three webinars to receive your free ‘Get Published’ eBook and course completion certificate.
  • 5 ways to successfully commercialise your intellectual property
    5 ways to successfully commercialise your intellectual property Annelie Viksten from AWAPatents | Carol David Daniel from City University | Duncan Clark from PatSnap Recorded: Feb 14 2018 59 mins
    In this webinar, PatSnap will be joined by Annelie Viksten, Carol David Daniel and Duncan Clark to explore what ingredients are needed to create an environment that promotes the best possible chances of market success for new projects.

    Other discussion points include:

    - The importance of a fully integrated, end to end commercialisation strategy
    - How to identify the differences between projects that create new revenue, versus those that don't.
    - How to extract more ROI from your existing intellectual property
    - Understanding the difference in approaches to innovation in academia, and the commercial world.
  • Efficient execution of biologics manufacturing – The role of Finite Scheduling
    Efficient execution of biologics manufacturing – The role of Finite Scheduling Gloria Gadea-Lopez, Ph.D., John Maguire and Megan Rabideau Recorded: Feb 14 2018 47 mins
    The success of manufacturing relies on the availability of all the resources –personnel, materials, equipment, work instructions - , orchestrated in such a way that the operations proceed in an efficient and predictable manner. This article describes the implementation of a finite scheduling system for biologics production, the foundational work required prior to project launch, lessons learned, and benefits achieved from this deployment.
  • An introduction to best practices for refereeing a journal manuscript
    An introduction to best practices for refereeing a journal manuscript Professor Simon Cherry, University of California, Davis, USA Recorded: Feb 13 2018 45 mins
    Peer review is one of the most critical components of high-quality scientific publishing. It impacts on the timeliness, accuracy and clarity of research findings that—if published—will be accessible and visible to everyone for years to come.

    At its best, the peer-review process establishes whether the work makes a genuine and valuable contribution to the literature, and can remove errors and help authors to better explain their results and the significance of their work to the broad audience who may read the final journal article. At its worst, however, inadequate or superficial peer review can allow substandard work or poorly explained research to be published, which is to the detriment of the scientific enterprise. In addition, the peer-review process can also impede the publication of high-quality work through unnecessary delays or personal bias.

    The goal of this webinar is to address best practices for reviewing a journal manuscript and address some of the challenges and pitfalls that frequently crop up during the peer review process. This webinar is aimed at those new to serving as a referee for a scientific journal – whether that be more generally, within the field of medical physics, or for Physics in Medicine & Biology specifically.
  • Disposables – Suitability and Process Economy In Biopharmaceutical Manufacturing
    Disposables – Suitability and Process Economy In Biopharmaceutical Manufacturing Dr Joachim Walter Recorded: Feb 8 2018 38 mins
    Since the introduction of disposables and gaining popularity of Single-use Technology (SUT) for biopharmaceutical manufacturing there is nevertheless an ongoing controversial discussion on the advantages and disadvantages versus a conventional stainless steel environment.

    In a “classical” facility design any validation cost effort can easily be distributed to a considerable number of production runs thus contributing only to a non-decisive amount to the overall production costs. The scale for such plant is nearly unlimited as is the scale of operation. The “flexible” approach using disposables and single-use equipment offers significant advantages regarding changeover work and time thus a high throughput of different processes will definitely take profit as any cleaning and related validation and costly analytics doesn’t apply to a larger extent.

    Despite the potential benefits loudly advertised by the respective industry, these potential advantages derived from single-use equipment and disposables can be significantly diminished by lack of detailed process cost analysis, missing economic analysis and cost comparison between conventional and SU technologies as well as underestimating the cost of long term dependency on consumables. Due to missing appropriate standards, there is a widely non-compatibility between the equipment and consumables of the various suppliers, resulting in a strong dependence on the consumables of a single supplier once a single-use equipment has been purchased, curiously leaving some customers with surprise that they hardly have any room for price negotiations on the required consumables.
    This paper’s focus is on the very different arguments for the application of SU equipment and consumables, including advantages and limitations of SUT, understanding improvement of process robustness, contribution to lean production as well as environmental impact of disposables.
  • Building a Data Forever Architecture
    Building a Data Forever Architecture Erik Ottem, Director Product Marketing, Western Digital Recorded: Feb 6 2018 27 mins
    Unstructured data has evolved into a business asset, creating the need to keep more data longer. The growth and diversity of unstructured, in the form of large media files, metadata, and complex business documents have created a strain on traditional storage infrastructures and IT budgets.

    In this webinar, our industry expert Erik Ottem will discuss the expanding role of unstructured data, the shortcomings of traditional storage architectures and the building blocks to capture, store and preserve data at scale and throughout its entire lifecycle.

    Register today and learn how to build a data forever architecture so your data can become a competitive advantage rather than a burden.
  • Do Extractable Protocols Truly Help- An End User Perspective
    Do Extractable Protocols Truly Help- An End User Perspective Ekta Mahajan, Genentech/Roche Recorded: Feb 5 2018 66 mins
    Single Use technology is being used more each year in the biotechnology industry. However, extractables and their potential impact on product and patients continue to be one of the biggest challenges. The challenge is augmented by the lack of standardized methodology for suppliers to execute extractable studies that meets end user requirements. The end users are responsible and required by law to assess the impact of extractables and leachables on overall Product Quality and Safety. Due to lack of a standard, customized data had to be generated for/by each end users. This resulted in long lead times, higher costs and inefficient utilization of resources. Typically, the data generation and qualification of single use component can take up to a year, which can impact implementation of single use. BioPhorum Operations Group (BPOG) developed a standardized protocol9 for generating extractable data that would meet user requirements and simplify/reduce implementation time within industry. A standardized protocol gives confidence to suppliers that testing performed by them would meet end user requirements and enable faster implementation. Some suppliers shared the BPOG vision and proactively tested their single use components using BPOG protocol, which has helped expedite the use of their products.
  • Venezia – Reaching Beyond
    Venezia – Reaching Beyond Matthew Biagioli, MD Recorded: Feb 5 2018 61 mins
    Treating advanced-stage cervical cancer can be difficult without the right tools. Dr Matthew Biagioli will discuss a new option for reaching beyond the current constraints with the Venezia applicator for reproducible results and seamless integration into your current workflow.
  • Sharing and Promoting your Research- Wiley Learn to Publish Webinar Series
    Sharing and Promoting your Research- Wiley Learn to Publish Webinar Series Jennifer Deroche and Katy Dillon Recorded: Jan 31 2018 24 mins
    Maximise the impact of your published work! Find out more about sharing and promoting your research including SEO and Altmetrics.

    In the third and final webinar in our Learn to Publish series, our expert editors and marketers will cover:
    -What you need to do to get read, get shared and get cited
    -SEO in 4 easy steps
    -Title, Abstract and Keyword best practices
    -Tips for building links
    -Understanding Impact Factors and Altmetrics
    -Tools and resources available to help you share and promote your work
    We’ll also be answering your questions in a live Q&A.
  • Need to validate your genome editing experiment? LentiORF to the rescue!
    Need to validate your genome editing experiment? LentiORF to the rescue! Stacey Ward, PhD Recorded: Jan 24 2018 47 mins
    Whether you are looking to perform gene overexpression studies or validate gene knockdown/knockout results from your RNAi/CRISPR experiments, LentiORFs are your ideal shortcut to protein expression and gene analysis. These genes are available in either pooled or arrayed libraries, and can also be combined into gene family sets and custom clone panels to meet diverse research needs. They are excellent reagents for gain-of-function screens and are a powerful complement to CRISPR and RNAi. In this webinar, we will introduce the LentiORF library and its various formats. We will discuss the application of this technology as it pertains to experimental design, delivery mechanisms, data analysis and target validation. Further, we will present recent data demonstrating clone representation of the library in each of its available formats, along with functional validation of the viral particles at the level of both viral integration and functional RNA expression.

    Our ready-to-use Mission TRC3 LentiORFs allow for stable integration, enrichment of cells, and long-term gene expression in difficult-to-transfect cell lines utilizing our best-in-class lentiviral manufacturing. This collection provides researchers with unique tools to gain insights into gene function by modulating gene and protein expression.
  • The Picture Perfect Future of the US Medical Imaging Industry
    The Picture Perfect Future of the US Medical Imaging Industry Frost & Sullivan Transformational Health Team, Shannon Werb, vRad Recorded: Jan 23 2018 62 mins
    The US medical imaging industry is transforming to cope with the challenges of the present and the demands of the future. The current care provision landscape is highly fragmented, and a coherent strategy is required to enhance interoperability among stakeholders across the imaging ecosystem. Stakeholders across the industry must also come together to eliminate redundancies and duplications, and streamline the imaging process, to improve the patient experience.
  • Publishing Ethics: understanding the dos and don’ts of research publishing
    Publishing Ethics: understanding the dos and don’ts of research publishing Dr Andrew Moore Recorded: Jan 22 2018 47 mins
    Learn more about what happens once your research article submission has been accepted
    •What are the author’s responsibilities?
    •What do ethics in publishing looking like?
    •What constitutes ethical misconduct?
    •How do ethics support authors?
    •What are the golden rules?

    Join us for our live webinar clinic and learn all you need to know about publishing ethics, what they are, why they exist and how to successfully navigate through them.
    Plus a chance to interact with the Editor-In-Chief for the Wiley Researcher Academy, Dr Andrew Moore and ask any further questions about the platform during the live Q&A sessions and connect with other researchers in the BrightTalk community.

    Register for our FREE webinar now and you’ll receive guidance on:
    •Ethics within scientific publishing
    •Your roles and responsibilities
    •What support and guidance tools are available
    •Navigating ethical challenges
    •The dos and don’ts of research publishing
  • Introduction to searching/using Markush structures from Patents
    Introduction to searching/using Markush structures from Patents Roshan Jumnah and Ruta Sudmantaite @ PatSnap Recorded: Jan 17 2018 34 mins
    Chemical Patents are often very long and difficult to read. Markush searching can enable you to easily categorize and filter the information you need, giving you the insights that a paper sometimes cannot.

    In this webinar you will learn:

    -How to get started with patent search
    -Basic patent language you need to be aware off
    -How to create Markush searches to yield the best results when researching.
    -Benefits of patent search for your processes
  • Enabling comprehensive data analytics and process monitoring in Biomanufacturing
    Enabling comprehensive data analytics and process monitoring in Biomanufacturing Robert Dimitri and Gloria Gadea-Lopez, Ph. D Recorded: Jan 17 2018 48 mins
    Technical teams rely on the availability of meaningful data and effective tools to perform process monitoring, to conduct root cause analysis and investigations and, most of all, to obtain new insights into their operations. In this article, the authors discuss the implementation and management of a comprehensive system for data analytics at Shire –Lexington, MA site, the lessons learned, and practical advice towards the successful deployment of these key applications.
  • Estimating respiratory rate from the electrocardiogram and photoplethysmogram
    Estimating respiratory rate from the electrocardiogram and photoplethysmogram Dr Peter H. Charlton Research Associate, King’s College London Recorded: Jan 16 2018 44 mins
    Respiratory rate (RR) is a key physiological parameter that is used in a range of clinical settings for diagnosis and prognosis. Despite its importance, it is usually measured by hand. Over the past 50 years many techniques have been developed to estimate RR from two widely acquired physiological signals: the electrocardiogram (ECG) and the pulse oximetry signal (photoplethysmogram (PPG)). Although these techniques have been the subject of much research, they have not yet been widely integrated into clinical practice. This webinar will provide a comprehensive overview of the state of the art in estimating RR from the ECG and PPG. It is intended to equip researchers with the knowledge and tools to translate this promising technology into patient benefit.
  • Current and future applications of Near-infrared in Pharmaceutical and Biopharma
    Current and future applications of Near-infrared in Pharmaceutical and Biopharma Dr Erik Skibsted 7 Dr Fabien Chauchard Recorded: Jan 10 2018 68 mins
    Near-infrared has a long tradition as analytical technology in pharmaceutical industry. In this article/webinar new applications, technology and improvements in regulatory guidances will be presented which will support further growth of nearinfrared in the pharmaceutical and biopharmaceutical industry.
  • Plan Explorer; An Automated Treatment Planning Approach
    Plan Explorer; An Automated Treatment Planning Approach Björn Hårdemark, Deputy CEO, RaySearch Laboratories Recorded: Dec 20 2017 61 mins
    Plan Explorer provides a new paradigm in treatment planning. This talk goes through the underlying algorithms, explains how to use the system, gives examples of plan configurations and provides an outlook into future developments of this feature found within the RayStation treatment planning software.
  • Digitizing Clinical Research Processes - The New Frontier
    Digitizing Clinical Research Processes - The New Frontier Cedars-Sinai's Research Manager, Jenny Lester, and Associate Director, Therica Miller Recorded: Dec 18 2017 58 mins
    Clinical trial enrollment and site initiation is often hindered by cumbersome onboarding paperwork, delaying clinical research and R&D investments. The good news? Cedars-Sinai's Research Manager, Jenny Lester, and Associate Director, Therica Miller have solved the issue by going digital, leading to accelerated processes and greater compliance with regulations like 21 CFR Part 11.

    Watch this on-demand webinar now and learn how to:

    -Overcome challenges in clinical site initiation & maintenance
    -Implement a pilot to test effectiveness of new digital processes
    -Identify and activate use cases for digital investment
  • Total Nitrogen Test Kits as an Alternative to TKN, Nitrate, and Nitrite Tests
    Total Nitrogen Test Kits as an Alternative to TKN, Nitrate, and Nitrite Tests Taylor Reynolds; Ed Askew Ph.D. Recorded: Dec 14 2017 48 mins
    Currently the US EPA has not promulgated a method for the analysis of Total Nitrogen (TN). Most states that have TN regulations require permitee's to measure TN as the composite of TKN, Nitrate and Nitrite. This approach is costly, time consuming, and also susceptible to variability based on the methods used for the individual analytes Merck, KGaA, Darmstadt, Germany is excited to announce the introduction of a Total Nitrogen Test Method consisting of a single spectrophotometric test kit. The method has been evaluated in a multilab study and this webinar will present the results of that study as well as an overview of the savings made possible by utilizing this new method for testing Total Nitrogen.
  • Rapid Fontana-Masson Staining
    Rapid Fontana-Masson Staining Vikas Palhan, PhD, Senior R&D Scientist, Emerging Biology - Genomics Recorded: Dec 14 2017 23 mins
    In the continued effort to save you time and simplify your workflow, we’ve developed a Fontana-Masson Staining Kit with a protocol that is 30x faster than the standard protocol. In this webinar, the researcher who developed the kit explains how easy it is to use this new rapid microwave technique. If you need to stain melanin and argentaffin cells in tissue sections, take a few minutes to watch this webinar - and save yourself many more minutes in the future by using this kit.
  • Transforming Access to Medicines Through Patient-Centric Solutions
    Transforming Access to Medicines Through Patient-Centric Solutions Dominic Tyer Recorded: Dec 14 2017 59 mins
    As medicines access evolves and pharmaceutical companies take an increasingly nuanced approach to it, it’s ever-more important to focus on particular aspects of this area and investigate whether firms are operating optimally.

    To do this Inceptua Medicines Access and patient group, HAEi, in association with PMGroup, will host a free webinar on Thurday 14th December that will cover both the pre-approval access to medicines and the importance of putting patients at the heart of drug development and access.

    Pre-approval access - a transformational approach
    There are a number of factors at play within the world of medicines access: from industry who need to navigate requests for their pre-approval and unlicensed medicines, to healthcare professionals who are looking for options for their patients and ultimately to the patients and patient advocacy groups who are more empowered than ever and are driving for more timely access to treatments. Today’s healthcare, political and regulatory environments burden have generated a rapid, increasing and significant expansion in the need for access to these medicines. Mark Corbett, Executive Vice President at Inceptua Medicines Access talks about the company’s transformative approach to medicines access, designed to rise to the evolving challenges of the environment, offering unsurpassed understanding and insight into the needs of biopharmaceutical companies and healthcare organisations.

    Patients at the heart of drug development and access
    If you believe the news every day, patients are becoming more and more involved in drug development and access pathways, but what does this mean in reality
  • 2018 Global Healthcare Market Predictions Revealed
    2018 Global Healthcare Market Predictions Revealed Reenita Das, Partner, Kamaljit Behera, Industry Analyst, Neil Jordan, Microsoft, Kay Eron, Intel, Keith Bigelow,GE Healthcare Recorded: Dec 13 2017 60 mins
    2018 will be a tipping point for mainstream adoption of popular digital health technology solutions such as artificial intelligence, mHealth/wearables, telehealth, Big Data analytics, and robotics. The transition of technologies from ideation to actionable applications will drive new opportunities across the globe.

    From data monetization unleashing the power of patient data to digital transformation of patient monitoring, there will be growing awareness of current inefficiencies and new opportunities identified to improve the efficiency of healthcare delivery.