The medical research community on BrightTALK brings together medical and research professionals. Find relevant webinars on medical research, laboratory science, continuing medical education and more presented by recognized medical researchers. Join the conversation by participating in live webinars and round table discussions on the latest in medical devices, medical research practices and trends in the healthcare industry.
Learn how Jocelyn Kolb-Dewitt and Darlene Farris-LaBar, co-directors of the G3D Stratasys Super Lab at East Stroudsburg University, inspire and empower students in art and design with 3D printing. Darlene Farris-Labar designs and 3D prints plants and flowers to reimagine an ecosystem on the brink of extinction. Explore product design with Jocelyn Kolb, who 15 years ago implemented 3D printing into her art and teaching. Analyze and understand how young minds interface software and hands-on learning for increased retention. Assess the impact of real-world projects including robotic prosthetics, DICOM scans, clothing design, biological models and artistic representations of microscopic life forms.
Join us and PHOENIX group as we delve into the concept of current launch excellence and the role of patient insights in overcoming the multiple challenges the industry currently faces.
Key topics to be discussed include:
– The challenges of launching a product in Europe
– How pharma can improve its understanding of the process through the use of business intelligence
– How insights from new data can be applied to the process of launch excellence
– The role of real-world data in launch strategy
– The downstream effect of applying real-world data to product launch on patient outcomes.
Dr. Rybicki is Professor and Chair of Radiology at the University of Ottawa and Chief of Medical Imaging at The Ottawa Hospital. In this webinar, you’ll examine the role of 3D printing in medicine and hospitals. Learn about use cases and different models for hospital-based 3D printing including facial transplants, surgical guides, radiology and standard research tools. Dr. Rybicki illuminates current trends and future direction in 3D printing while addressing parallel topics such as costs, education, printer selection and achieving objectives.
Working with QuintilesIMS, we present a digital debate which will offer modellling-based insights into the future of hepatitis C treatment.
Key topics to be discussed include:
– The burden of HCV
– The current market landscape
– The current patient access model and its impact on budget
– Cost efficiencies shown by modelling
– Cure versus lifetime treatment costs
To celebrate the 30th anniversary of the Nobel prize in scanning tunnelling microscopy (STM) and the 30th anniversary since the first paper in atomic force microscopy (AFM), Nanotechnology™ has been organising a focus collection with guest editors Franz Giessibl, Rodolfo Miranda and Johannes Barthes to collate some of the latest cutting-edge progress developing and exploiting these scanning probe techniques.
In this webinar, we invite one of the guest editors of the collection, members of our editorial board and authors of contributions in the collection itself to join our panel to look at some of the highlights in STM and AFM over the past 30 years and some of the most exciting research developments in the field today.
Immuno-oncology therapies that harness the body’s own defences to fight tumours are widely acknowledged as the new frontier in cancer treatment, but until recently only a few products had reached the market for a limited number of indications.
Over the past 12 months several new products have been approved for a wider range of tumour types and with pipelines boasting numerous other products in the area, competition looks set to hot up.
On November 17 Research Partnership, in association with PMGroup, will host a free webinar which will explore the key features of the immuno-oncology market and the critical success factors for remaining competitive.
I would like to invite you to register for the webinar - either to watch it live on the day or for access to a recorded version.
In this webinar, Dr. Michael Samoszuk will discuss how red blood cell data reported from urine chemistry test strip analysis can correlate to red blood cell data gathered from the microscope, even when the data appears to be conflicting. Attendees will discover some of the underlying factors that could cause this to occur and learn how to minimize reporting inconclusive or inaccurate results.
The CRISPR/Cas genome editing system has revolutionized almost every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA, or lentivirus. Each reagent has been successful in its own right, however, each approach has limitations. SygRNATM, the two-part synthetic crRNA and tracrRNA, increases the pace of research, decreases costs, and can be used with Cas9 protein, Cas9 mRNA and Cas9 expressing cells/models.
This webinar discusses the development of the SygRNATM system, protocol optimization, and proposes workflows that enable scientists to quickly incorporate CRISPR technologies into their research.
Over the past 20 years, behavioural economics has identified factors that influence and determine how people behave, including alternative decision-making pathways and many cognitive biases and heuristics. Taking account of these helps to build a clear view of how healthcare customers think and behave in relation to your product in the real world.
This short masterclass explores ‘quantitative demand assessment research’ – what it is and how insights from behavioural economics can improve the application of this important tool in pharmaceutical market research.
The masterclass will:
•Introduce demand assessment research and why it is important to healthcare market research
•Discuss how insights from behavioural economics can improve quantitative demand assessment market research
•Highlight a range of techniques using behavioural economics that help you build a more accurate picture of your customers and market.
This webinar aims to highlight the benefits of correlative Raman imaging for the analysis of chemical composition, crystallinity, stress and optoelectronic properties of materials such as semiconductors, 2D materials and electrodes. Used in combination with either atomic force microscopy or scanning electron microscopy, Raman correlative microscopy provides deep insight into the relation between molecular and structural features of materials – even in 3D.
The principles of state-of-the-art confocal Raman imaging will first be introduced, then its power as an ideal tool for investigating the chemical and molecular characteristics of a sample will be demonstrated with examples of 2D materials, semiconductors and battery electrodes. The webinar will describe clearly the advantages and ease- of- use offered by Raman imaging systems integrated with other microscopy technologies.
H&E is the most frequently used stain in histology and is the basis for diagnostics and further selected methods. Thus it is important to have brilliant staining. We will show which minor factors can give a negative effect or spoil the result completely. Tips will be given on improving the sensitivity of the stain. For PAS, we will give advice on how to avoid common errors and always get colourful results.
We will discuss:
•How to prevent "critical situations"
In part one of this webinar, Freddie Cardel outlines the concept of automatic plan generation with Plan Explorer and demonstrates a completely new level of automation. He explains the approach, where large numbers of high-quality treatment plans are automatically generated for defined clinical goals and combinations of treatment techniques and machines, and shows how these plans can be easily filtered and browsed to find the most suitable candidates to be evaluated.
In part two, Erik Korevaar and Roel Kierkels present the first findings of the clinical evaluation they performed at University Medical Center Groningen, the Netherlands, and describe how the center envisions the use of the tool in clinical practice.
Most life sciences companies know they need to move their multichannel marketing forward, but that requires managing a greater volume of tactics that need to be developed, approved, implemented, and measured.
And of course, those tactics must reflect how their target audiences engage in content – such as the 65% of healthcare professionals who say they prefer clinical summaries.
To truly transform the commercial model, companies must have a strategic blueprint that combines business objectives with brand goals to determine the appropriate resource levels and channel attribution.
On November 9 Aptus Health, in association with PMGroup, will explore three essential ingredients for transforming the commercial model and driving success:
• Learn how to deploy multichannel marketing at scale through integrated campaigns that reach millions of HCPs across specialties, languages, and markets
• Gain insights into your target HCPs’ behaviours - and how to leverage those insights to make your campaigns more effective
• Explore results from a recent survey of European HCPs revealing their preferences for the types of online medical education, as well as the resources they find most helpful in their daily practice
Across the globe, omega-3 intake is lower than recommended. This means a large proportion of the population is missing out on the wide range of health benefits offered by omega-3s. Omega-3s have been linked to the reduction of the risk of cardiovascular disease, which is responsible for more deaths worldwide than any other condition.
Join us for the next in our webinar digest series to hear Prof. Philip Calder, DSM’s Prof. Manfred Eggersdorfer and Brent MacDonald, discuss how omega-3s can help reduce the risk of cardiovascular disease.
Webinar: The Impact of Soluble Factors and Substrate on Cell Culture: Media Additives, Growth Factors, and Surface
From basal media with feeder layers or serum to highly defined recombinant growth factors, cytokine, and extracellular matrix, there are many ways to grow the same cell type. The choice is dependent on scale, cost, control, skill, and regulatory factors.
This webinar will cover:
- Different ways to grow the same cell type
- The actual material costs of various methods
- Methods used to optimize formulations
Kevin Kelly graduated from Hawaii Pacific University and for 15 years worked on process scale-up and optimization for extracellular matrix proteins, growth factors, cytokines, antibodies, ELISA kits, and Corning® BioCoat™ products.
Currently he provides applications support for invasion, migration, permeability, transport, differentiation, and metabolism assays.
Continuing our series of webinars showcasing presentations from the PMB 60th Anniversary Symposium, Brian Pogue discusses the evolution of diagnostic imaging over the last 60 years. He will present examples of successful medical imaging technologies, explain how the use of contrast agents can improve delineation and function assessment, and present some fundamentally new physical imaging systems.
In research areas such as academic, biofuel, food and pharmaceutical industries the determination of algal viability, lipid content, and cell concentration is important in the selection, monitoring, and maintenance of algal cultures. Flow cytometry has been shown to be an ideal method to assess health and lipid content of cultures but has been challenging to adopt due to high complexity and cost of traditional technologies. In this webinar, we present novel simplified methods for algal characterization using microcapillary cytometry on either a simple touch screen based cytometer, the Muse® Cell Analyzer, or a higher throughput cytometric platform, the compact Guava® easyCyte platforms. The MilliporeSigma algae kits utilize simple mix and read protocols, dedicated software modules, and provide quick results for the of count and viability measurements or relative lipid content on algae strains. The optimized and dedicated algae kits allow for high precision and comparable results to predicate methods. Data from applications to multiple common algal strains such as Chlorella vulgaris and Chlamydomonas reinhardti under different culture conditions will be presented. Availability of dedicated kits for algae research on simple and easy to use cytometric platforms will empower and enable algae researchers to rapidly select optimal culture conditions and strains for downstream experiments.
If you're publishing scientific work, applying for grants, or just want to better convey your research to a wider audience you need to join us for this special webinar with authors Sam Illingworth and Grant Allen on their book Effective Science Communication: A practical guide to surviving as a scientist.
Sam and Grant will talk us through the research behind their book, why they feel there is a need for this, and provide advice on not only how to survive, but to prosper in the process.
There will be a live Q&A session at the end of the webinar.
Commercial analytic solutions are becoming more and more common within the Pharma industry. Companies are spending millions implementing tools which are aimed at helping users identify opportunities to improve the bottom line, segment customers, track multichannel campaign success and meet a myriad of other objectives. Despite all the 'perceived' value these tools can add, they remain largely unused. Excuses for the lack of adoption are varied but can generally be classified into one of three areas - they are either too complex, it isn't convenient to use or it just doesn't deliver on the value promised. These issues are compounded by the fact that they are generally only identified when the solution has been deployed and expected to be used. By ensuring that these issues are addressed at all stages during the development and not just when adoption targets are not being met, commercial analytic solutions can be exploited to attain the anticipated value and more.
Join us as we share some exciting new initiatives and discuss what’s to come in the remainder of 2016 and in 2017. We’ll also be giving updates on content coverage and content curation programs, as a lot has happened since we last presented on Scopus content in February. Tune in to stay current on all there is to know about Scopus - the Gold Standard multidisciplinary abstract and citation database.
Join expert medical librarian Amanda Horsman and Doug Felder from Mendeley for an exclusive webinar focused on how librarians like you use Mendeley Institutional Edition to support students and researchers. Amanda will demonstrate the power of facilitating inter-professional collaboration between research group members.
Extreme Light Infrastructure – Nuclear Physics (ELI-NP) is the most powerful laser system dedicated to laser-matter interaction and nuclear physics studies. With a recent investment in creating a new cutting-edge research facility ELI-NP is now seeking the very best minds to join their crew in Romania.
Join Nicolae Victor Zamfir, Project Manager at ELI-NP, to discuss the incredible work being done in understanding the fundamental processes involved in light-matter interaction. You'll find out about the new opportunities available as well as:
- what ELI-NP is looking for in your application
- the benefits of working for ELI-NP
- how to apply
Discover how to promote your research, receive practical tips for working with the media and learn more about boosting your own research profile.
In this webinar you’ll receive the practical advice you need to ensure you work effectively with your institution or publisher to promote your research. Hear why you should get involved in Standing up for Science throughout your career and understand how to responsibly communicate with the media.
Hear from experts at Wiley and Sense About Science on:
•How to make your research have an impact
•Assessing how newsworthy your research is – finding the ‘hook’
•Understand how the media works and receive practical advice on working with journalists
•Your role as a scientist in society and the importance of sharing your research
•Responsible communication of your research
This webinar addresses practical computational issues in discrete calculations of the path of charged or multipole particles in electric and magnetic fields.
We begin by showing the theory and an Excel macro implementation of some standard ODE time-based solvers as applied to the charged-particle case. We also discuss potential benefits of a nonstandard distance-based solver configuration.
Next some examples are provided to illustrate trade-offs between the number of calculations and the accuracy of the result according to various criteria. For example, depending on one’s needs, the simulation set-up might produce output that is either a dense set of (x, y, z) points that plot as a smooth curve, or a much sparser set of points that are individually more accurate than the dense set.
The webinar will end by examining what can be done with the data obtained. Calculations based on a linear interpolation between points are straightforward, but may force one to use an inefficient ODE set-up. This can take excessive computation resources, hence a longer time than necessary to produce accurate results. Some alternatives will be demonstrated using various degrees of physical insight to get the most information possible from the given ODE output data.
In this webinar, Dr. Michael Samoszuk will discuss the correlative relationships between urine chemistry analytes and the particles noted under the microscope. Attendees will learn how using the knowledge of these correlations can optimize parameter setting for improved laboratory workflow.
With rising healthcare costs, more informed and engaged patients, and advancing technology, health wearables have seen a significant uptake in recent years. However, the full potential of health wearables has yet to be recognised and there are still challenges to be resolved. What needs to be done on the regulatory, technical and healthcare side to take health wearables to the next level?
In this webinar, experts from the life sciences and technology industries discuss their views on the current state and future developments of health wearables, including:
– The user perspective: perception, adoption and expectations today and tomorrow
– The technology perspective: biggest successes and most room for improvements
– The societal and regulatory perspective: cost and risks versus benefits and opportunities
In the third of our webinars showcasing presentations from the PMB 60th Anniversary Symposium, Bas Raaymakers examines the use of image guidance during radiation therapy. He will describe the various options available for radiotherapy guidance, including in-room CT-on-rails, MV imaging, fluoroscopy, ultrasound, tracking of implanted beacons and cone-beam CT. In particular, he will discuss the use of MRI for real-time visualization of the tumour and its surroundings during treatment.
The atomic force microscope (AFM) has played an essential role in 2D materials research since it was used to confirm the first isolation of graphene. Today’s AFMs are even more powerful, with higher spatial resolution, faster imaging rates, greater environmental control and enhanced modes for mapping physical properties. They can image crystal lattice structure as well as nanoscale morphology, and sense local electrical, mechanical and functional response in more ways than ever before.
In this webinar we explore the latest AFM tools that enable higher resolution, sensitivity and more quantitative results for analysing 2D materials. We’ll present results from measurements of a variety of 2D materials for device manufacturing, energy storage and optoelectronics including:
• MoS2 and graphene;
• measurements of mechanical properties;
• kelvin probe imaging (KPFM) of operating transistors;
• electromechanical measurements.
Finally, we discuss how AFM can now be used to accurately determine the thickness of single or multiple layers of a 2D material. This will challenge the misconception that AFM cannot be used to precisely measure the thickness of 2D materials.
Resource constraints, financial and human, mean that most universities simply do not have the luxury of being able to back every research commercialisation opportunity. Therefore, it is essential to develop a strategy and process that optimises the chances of backing winners, be it to maximise the financial return or to address the non-financial impact agenda.
PatSnap will be teaming up Isis Enterprise, the innovation consultancy division of Oxford University Innovation, to discuss some key measures that can be taken to identify promising commercialisation projects that are underpinned by strong intellectual property. We will also be providing insight on methods for trimming and shaping academic patent portfolios so that they are optimised for strong overall returns.
Gene Quinn and special guests look back at the most important moments of 2016, and consider the issues that look set to shape the patent industry in 2017
It is that time once again when we look back on the previous year in preparation to close the final chapter on 2016, and we begin to look ahead and ask what is in store for the new year.
Gene Quinn, patent attorney and founder of IPWatchdog.com, will moderate this discussion, alongside a panel of very special guests.
Join us as we discuss:
2016: The Year of the Patent Trial and Appeal Board – From the Supreme Court deciding Cuozzo, to the Federal Circuit spending much of the year rubber stamping the PTAB, it has been a rollercoaster year.
2016: Software Patents Strike Back – A series of Federal Circuit decisions post-Alice have started to provide meaningful insight into how software can be described so that it will be considered patent eligible.
2017: Regulatory Reform NOT Patent Reform – Patent reform will almost certainly not be a top priority for the Trump Administration, but regulatory reforms to the PTAB could be seen and may be quite significant and beneficial to patent owners.
2017: Supreme Court to Decide Samsung v. Apple - The decision will either validate the value of design patents or make design patents virtually worthless.
In this webinar, Dr. Michael Samoszuk will discuss the correlation between images of urine sediment particles captured on the iRICELL3000 and images viewed manually under the microscope using actual patient samples. Attendees will learn how these images compare and how automated microscopy helps to reduce user subjectivity in microscopy by standardizing the process.
Despite the economic slowdown in Asia-Pacific, the healthcare industry continues to grow with increasing healthcare spending across all countries, albeit at varying levels. Acceptance of concepts like value-based care and preventative care is creating a demand amongst consumers and healthcare providers for new technologies and innovative care delivery platforms, while pressuring industry participants like pharmaceutical and med tech companies to reinvent their business models. Unfavorable doctor-patient ration, disparity in healthcare access, rising incidence of chronic and infectious diseases, and an underserved primary care landscape are examples of how healthcare can be brought closer to the consumer.
Single-Use Process Analytical Technologies (PAT) tools have a great potential to not only increase process understanding at the seed stage but also simplify cell culture operations. By utilizing PAT, the risk from bioburden or contamination can be significantly reduced and the overall operating efficiency increased. In fact, PAT also provides a data-driven platform to integrate Process Development and Manufacturing Operations that can mitigate risks associated with technology/process transfer.
The healthcare industry is undergoing rapid transformation. By 2025, the healthcare ecosystem is expected to look drastically different from today. In 2025, global trends of aging populations, rising chronic disease prevalence and urbanization are bound to further strain healthcare systems already grappling with issues of healthcare access, quality, and cost. In response, new business models are expected to emerge to address the needs of the future. In order to make the most gains, stakeholders must successfully leverage this transformation.
Continuous bioprocessing offers potential to enhance productivity and product quality uniformity while simultaneously decreasing facility footprint and associated operational overhead. Advances in technology and increasing commercial pressures are leading to an increased interest in continuous processing across the biopharmaceutical sector. A number of companies are exploring and advancing continuous bioprocessing and this presents a range of opportunity and challenges, including the use of Process Analytical Technology (PAT) for process characterization, process control, and process robustness, in support of a Rapid Product Release (RPR) strategy.
Sourcing for the manufacture and control of Antibody-Drug Conjugates (ADCs) used in clinical trials requires strategic planning, establishment of a specialized support network, and execution of several interdependent tasks. ADCs are complex molecules, a fusion of a biological, the monoclonal antibody (mAb), and of small molecules, the linker and the toxic payload. Facilities of acceptable standards for the handling of high potency materials need to be engaged, and there is a limited supply currently. This is further complicated by the fact that there is not one contract facility that has fully integrated services, a “one-stop shop” capable of mAb production, linker and/or payload synthesis, conjugation of mAb to linker-payload to make the Drug Substance, and finally, formulation of the ADC to make the Drug Product. Strategizing the best outsourcing practices for producing and testing ADCs, and establishing guiding principles for externalization to ensure the selection of the right CMOs for ADC outsourcing and technology transfer, will be further discussed.
Observable foreign and particulate matter has for a long time been recognized as a critical quality attribute for production of injectable protein formulations. Recently, a focus shift towards these particles and even smaller particles (particulate matter or subvisible particles) has been seen from the pharmaceutical industry, academia and the different regulatory bodies. Two of the central documents in this context are:
1. The FDA Guidance for Industry on Immunogenicity Assessment for Therapeutic Protein Products1 and
Comparability exercises are commonly required at certain milestones during drug development as well as after product registration when changes are implemented into the manufacturing process. The goal is to evaluate if the product remains highly similar (not necessarily identical) before and after the change in terms of quality and stability and have no adverse impact on safety and efficacy predicted for the patients. This assessment requires product-specific knowledge gathered through drug development, taking a totality-of-evidence approach. The different levels of information are obtained from analytical studies for characterization of the molecule, animal studies for toxicity, pharmacokinetics and pharmacodynamics for pharmacological activities, and clinical studies for safety/tolerability, immunogenicity and efficacy. This Webinar discusses strategies and considerations for analytical characterization of protein structure and function which forms the foundation of the comparability demonstration.