Yvonne A. Reid, Ph.D.
The misidentification of human cell lines in research labs is a significant problem that may be costing the scientific community millions of dollars annually. Authenticating human cell lines is a crucial, yet underappreciated, quality control step for researchers performing cell biology, genetic mapping, gene expression, and gene therapy research. The validity of conclusions drawn from research data is dependent on consistent and unequivocal verification of cell line identity and function. Over the past 50 years numerous human cell lines have been shown to be misidentified due, in part, to poor cell-culture technique and inadequate authentication protocols. Technological advances have given rise to improved authentication capabilities.
This one-hour presentation will provide an overview of the current technologies used to authenticate human and animal cell lines.