Vitaly Klimovich, Ph.D.
Multiple cell-based applications require large numbers of cells. Traditionally, researchers used a common paradigm and choice of vessels for scaling up adherent cell culture. With the introduction of Corning® High Yield Performance (HYPER) technology, a new scale up approach became available. The principle of operation of the technology is based on the use of a gas permeable film that serves not only as the cell growth surface, but also as the site for gas exchange for adherent culture. The first vessel featuring gas-permeable film, HYPERFlask®, was introduced by Corning several years ago. The volumetric footprint of HYPERFlask is equal to traditional T-175 flask, but allows to grow ten times the number of cells, thus saving valuable incubator space. The Corning proprietary CellBIND™ surface allows to achieve superb cell attachment and performance. Recently, Corning has introduced HYPERStack® -- a line of cell growth vessels combining the footprint of Corning CellSTACK chambers and advantages of gas-permeable technology.
This seminar will discuss the unique features of HYPER technology and technical aspects of its operation; advantages and usage of HYPERFlask and HYPERStack vessels; and provide solutions for optimal use of this novel technology in your scaling up needs.