Search results Search for: Search Refine your results by duration: Any Under 5 mins Under 20 mins Over 20 mins Sort by: Relevance Views Date How to Make Preclinical Research a SUCCESS Dr. Anthony Brown - Carrick Therapeutics; Dr. Allan Jordan - Sygnature; Dr. Dima Kuzmin 4BIO; Dr. Alex Moreau - Champions Join the revolution in drug development, based upon forward thinking study design and experimental approaches that are predictive of drug candidates d... 1 year ago | 90 mins Targeting Notch Altered Patient Derived Xenografts (PDX) with AL101 Joel Kaye, PhD, VP Research & Nonclinical Development, Ayala Pharmaceuticals Notch pathway activation has been implicated in the development of cancer. Notch cleavage by γ-secretase frees the Notch intracellular domain (NICD), ... 2 years ago | 28 mins Human-derived IO preclinical systems—from in vitro to in vivo and back Amy Wesa, PhD, Head of R&D, Champions Oncology Immuno-oncology (IO) is the study and development of treatments that take advantage of the body’s immune system to fight cancer. IO research has been ... 2 years ago | 39 mins Next Generation Humanized Mice for AML and NK Cell Therapy Testing Amy Wesa, PhD, Director of Immuno-Oncology Research at Champions Oncology To develop the most successful novel agents for cancer, researchers require preclinical models that fundamentally epitomize patient populations to ena... 2 years ago | 56 mins Cell cycle intervention beyond Palbociclib; discovery of a CDK2/4/6 inhibitor Stephen Dann, PhD, Associate Research Fellow, Pfizer Phosphorylation of the retinoblastoma protein (RB1) by cyclin-dependent kinases (CDK) 4 and 6 is a critical checkpoint for G1/S cell cycle progression... 2 years ago | 51 mins Selective Ablation of Malignant Cells using Apoptotic Gene Therapy Jailal Ablack, PhD, Head of Preclinical Research, OncoSenX While chemotherapy is a key treatment strategy for many solid tumors, it is rarely selective for tumor cells. OncoSenx has developed an effective suic... 2 years ago | 34 mins Rare Oncology Research in the 21st Century Sachin Kulkarni and Juliet M. Moritz Study of rare cancers tends to look more like rare disease research than standard oncology research. This webinar will highlight some of the challenge... 2 years ago | 61 mins Addressing Questions & Unmet Needs in Melanoma Research and Treatment Marc Hurlbert; Tom Williams The landscape for melanoma research and treatment has rapidly changed over the last decade. Since 2011, the FDA has approved 12 new melanoma treatment... 2 years ago | 60 mins Flow Cytometry: Validation and Implementation in a Regulatory Setting Chelsea Riveley, MBA, Head of Business Development, Flow Cytometry Services This webinar provides an overview of flow cytometry and its potential uses in the regulatory setting. Two case studies will be presented to detail the... 2 years ago | 56 mins Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck SCCs Francis Burrows, PhD, VP of Translational Research, Kura Oncology Tipifarnib is a potent and highly selective inhibitor of farnesyltransferase (FT). FT catalyzes the post-translational attachment of farnesyl grou... 2 years ago | 43 mins Load more
