Carolyn J. Otten, Ph.D. of Chemir Analytical Services will present case studies and strategies to solve challenging food, beverage and packaging problems including contaminant identification, packaging failures and extractables/leachables. Chemir is an independent analytical laboratory providing investigative testing services, chemical analysis and litigation support. For more information please go to: www.chemir.comRead more >
ICS environments are typically “flat”, designed with a rudimentary security posture never intended to be connected to the corporate network nor the Internet for that matter. The trend towards connectedness persists and this, along with the rising ICS threat landscape has made ICS a prime target for cyberattacks. Stronger access controls are critical for managing the different attack surfaces.
During this webinar you will hear from several ICS Networking and Security expert practitioners on how this connectedness can be securely and easily achieved:
· What “Zero Trust” is, how it scales, and why you would want to deploy this in your ICS along with the idea of positive enforcement for your security policies.
· How to bolster your network visibility and segmentation without having to do a “forklift” overhaul and reconfiguration of your existing infrastructure.
· How the Palo Alto Networks platform can help you realize these concepts in a systematic, organized, and minimally disruptive way.
Lionel Jacobs, Sr. ICS Security Architect, Palo Alto Networks
Information Security Architect, Major Food & Beverage Manufacturer
Del Rodillas, Solution Lead for ICS & SCADA, Palo Alto Networks
The European pumps market for the food and beverage industry witnessed a nominal growth in 2012. An increase in growth is expected over the next five years; the outlook for 2013-14 is likely to mirror the situation in 2012 due to the impact of the sovereign debt crisis in Europe. Centrifugal pumps have the bigger share of the market, but positive displacement pumps are likely to witness higher growth. Increasing consumer preference for convenience food is expected to be a key driver for the growth of the pumps market in the processed food segment. The increasing consumer awareness on the health and safety aspects of food products is expected to increase the emphasis on the hygienic aspects of the pumps during the forecast period and beyond.Read more >
In New Food’s upcoming webinar the analytical importance of colour analysis within the food industry, as well as examples of systems that can be used for colour measurement will be explained by three industry experts; Christian Jansen, European Sales Manager, Hunter Associates Laboratory, Inc., Thibaut Dedreuil-Monet, Technical Specialist, RSSL and Etienne Arman, Analytical Specialist, Jacobs Douwe Egberts (JDE) GB R&D Ltd.
Whether a food product is declared tasty depends on its ingredients, flavor and also the appearance of the final product. In many cases the first sense engaged when someone goes for a food product is vision. Especially with packaging the only way to judge if it’s a good product or not is optics. To measure colour hues of food products in a variety of conditions, complex technical solutions are required. Whether raw materials or solids and liquids, only special spectrophotometers can give precise data to help formulate colour and calculate values or differences. Length of a food process, ingredients, flavour and many more factors influence the appearance of a food product; with detailed analysis manufacturers can meet the ideal optical impression which is attractive for customers to buy the product.
This webinar will provide an overview on the topic of analyzing various fatty species in foods and methods to determine various classes from total fat to various lipid fractions and the wide variety of analyses available for fat determination. Topics discussed will include the analyses of fatty acid methyl esters (FAMES) in foods and the use of comprehensive two-dimensional gas chromatography (GC x GC) for the enhanced separation of highly complex mixtures. Advances in GC column stationary phases and new phases based on ionic liquid technology for the analyses of saturated and polyunsaturated FAMES will be discussed aswell as the use of GC×GC in the field of food lipid analysis. The considerable advantages of the two-dimensional approach (both with and without MS detection), in experiments related to a series of lipid volatiles (fatty acids, sterols, oxidation products, fatty alcohols, etc) will be illustrated.
In this webinar, we will:
> Overview the wide variety of methods available for the analysis of fat in foods.
> Examine traditional and new classes of GC Stationary Phases for the evaluation of various FAME species.
> Discuss the power of two-dimensional gas chromatography (GCxGC) for separating highly complex mixtures and how it can be combined with mass spectrometry for analyzing volatile and semi-volatile analytes
Energy and Sustainability Management in the Food and Beverage environment, reducing your Operating Costs, to Boost your Profit Margins.
Compared to other industries, the Food and Beverage (F&B) industry leads the way in terms of the development and deployment of sustainability programmes. F&B manufacturers have improved the efficiency of their facilities, invested in renewable energy, and managed the sustainability of their supply chains in order to lower the impact on the environment. The F&B industry has met the requirements of global and local legislation, and leads all sectors in sustainability disclosure.
However, with persistent global resource shortages and increasing energy and commodity prices, tougher governmental regulations will be enforced and customers will demand increased transparency of F&B operations. It is estimated that 10% of the world’s emissions come from manufacturing, and that a 26% improvement potential exists for manufacturing firms worldwide.
This Webinar, recommends an integrated Sustainability and Energy Management programme resulting in reduced costs, increased profitability, lower carbon emissions, mitigated risk and improved corporate image for F&B organisations.
Hygienic design, regulations & compliances are increasing dramatically in the Food & Beverage market. Consequently, the questions raised are: how can you ensure food safety? How does Hygienic Design support the cleanability & Total Cost of Ownership of your plant? And with a practical example: What does a perfect flowmeter for liquids look like?
As well as speakers from Bürkert, this webinar features presentations from Hein Timmerman of Diversey-Sealed Air & Patrick Wouters of Cargill. Both are members of the European Hygienic Engineering & Design Group, EHEDG.
Patrick will discuss Cargill’s overall goal to provide high quality, safe food, every time, everywhere; to this end, hygienic design is an important pre-requisite. This accounts for the choice of flow meters. Although hygienic design is a critical element, it is more important to have a correct measurement of the flow. This control point is of utmost importance, to ensure that specified functionality is achieved & food safety & product quality is ensured.
Hein will discuss Sealed Air’s Value Added Services on cleaning applications & cleaning validations, which includes remote monitoring tools & software platforms to support their end customers’ requirements for food safety & Total Cost of Ownership.
Bürkert’s John van Loon will discuss their new technology, FLOWave. This answers the hygiene issues other systems could face, by employing surface acoustic waves in a stainless steel tube. As such FLOWave allows a flow measurement of liquids without any parts within the tube. Current methods in industrial flow measurement are mainly based on moving parts like paddle wheels or rigid fixtures such as a bluff body in the measurement tube. These flow metering systems have their specific weaknesses, limiting their range of applications. The measuring task must be fulfilled, reliably, throughout the entire life cycle of the device. Also, the daily operative handling effort should remain within reasonable limits.
Water is the main ingredient in all of The Coca-Cola Company's beverages and is essential to its manufacturing processes. Water also has broad implications for the company’s supply chain as a key component in the production of sugar, citrus, coffee and other ingredients. It is also vital to the sustainability of the communities that the company serves. Reducing water scarcity, enhancing water quality and addressing the water needs of local communities are direct and vital business concerns.
Over the last ten years, the company's evolution in water stewardship has been significant: from a major reputation crisis in 2002 involving communities and government authorities in southern India to a 2007 call for corporate “water neutrality,” TCCC has developed and continues to evolve one of the more sophisticated water stewardship programs in the private sector.
However, true sustainability as it relates to water will involve more than “neutralizing” the volume of water that the company uses. This is because fluctuations in the amount and quality of water available to a given community or ecosystem play an important role in sustaining the diversity and proper functioning of river ecosystems and watersheds.
This presentation will profile Coca-Cola's experience over the past ten years providing a glimpse into the company’s commitments and an appreciation of the complexity of true water stewardship:
• Plant performance (water use efficiency, water quality, wastewater treatment)
• Watershed protection (source assessment and protection)
• Sustainable communities (helping enable access to clean drinking water and sanitation)
• Global awareness and action (helping mobilize the international community to drive global awareness and action to address water challenges)
In the 21st century, the primary challenge facing the entire global food & agriculture industry sector will be ensuring that it is intact into the 22nd century. Three themes emerge from the key challenges facing the food and agricultural industry sector that companies need to know in order to be successful in this market space today and tomorrow:
- Resource efficiency
- Changes to the socio-economic environment
- Freedom food and enhanced nutrition and health
This analyst briefing will argue that companies with a truly global market and product strategy, a focus on health and wellness, and adoption of an environmentally and socially responsible sustainability strategy will come out on top and be global leaders of the food and agriculture value chain. Join Frost & Sullivan as we present an assessment of the current trends and predictions expected to impact the global food and beverage market and enabling industries in 2015 and beyond.
Join internationally renown Food & Wine expert, speaker, writer and storyteller, as well as the CEO and Publisher of Food & Beverage International, Michael Walsh, for a tasty and tempting review of: The Best Food & Wine Pairings of 2008.
Besides be given the secrets to this holiday's greatest dinner combinations, you may pick up a few valuable merchandising tips as Mike has developed powerful in-store cross-merchandising programs that included Toy Wars, and The World’s Largest Chocolate Chip Cookie, utilizing in store mediums, such as grocery bags, and in store television.
He has not only produced for both television and radio but is also a radio talk show guest host.
Michael is an active food, wine and travel writer/photographer. Many of his stories can be found in Food&Beverage International, as well as California the Magazine. He currently serves on the advisory board of Great Wines International, and directs the tasting advisory board for Food&Beverage International, and www.fbworld.com.
Join Mike for the "Perfect Presentation" before the holidays, and don't forget to invite your Food and Wine Loving friends.
A webinar focusing on the three most widely used technologies: Incoming or Outgoing goods inspections, at-line production control and quality control for declaration purposes.
Processed food, beverage, feed or forage pass different steps in their production cycle requiring different technologies for the determination of nitrogen or protein. Whether you need fast qualification of raw material, or precise protein declaration of processed goods; Kjeldahl, Dumas and NIR solutions can be the methods to help you. There are many factors which influence the determination of the best fitting method. Whereas Kjeldahl is a proven method for all kind of sample matrices, Dumas excels in unattended processing at high throughput, and NIR is matchless in terms of immediate and comprehensive multi-component analysis.
This webinar will address the challenges that you are faced with in determining nitrogen or protein, and will present a range of technologies deigned to assist you in your processes.
Differential scanning calorimetry (DSC) is the most frequently used thermal analysis technique alongside TGA, TMA and DMA. DSC is used to measure enthalpy changes due to changes in the physical and chemical properties of a material as a function of temperature or time. The method allows you to identify and characterise materials. Differential scanning calorimetry is fast, very sensitive and easy to use. In this Webinar, we will discuss the basic principles of DSC and present some interesting applications.Read more >
Near infrared spectrometers have long been the PAT tools of choice for pharmaceutical and industrial scientists seeking to gain physical and chemical information from their samples. More recently, the development of fast and inexpensive miniature NIR instruments has greatly facilitated real-time in-line monitoring of multiple unit operations within a process. NIR can be used as a supervisory tool for multiple critical quality attributes of a drug product. Deviations from the acceptable ranges can be acted on in real-time based upon closed-loop control strategies.
This webinar discusses how miniaturised spectrometers facilitate testing of different control schemes with the goal of enabling real-time feedback control of continuous manufacturing processes.
> Chris Pederson, Product Applications Engineer, Viavi Solutions
Chris will present the principle of operation of the linear variable filter-based miniature NIR spectrometers, i.e., the MicroNIR Spectrometers developed by Viavi Solutions. He will also share key performance attributes of these ultra-compact MicroNIR products, and their applications in the pharmaceutical industry.
> Krizia M. Karry, PhD Candidate at Rutgers University (now with BMS)
Krizia will present results of the MicroNIR spectrometer and its application for testing various control schemes and enabling real time feedback control of a continuous manufacturing process for tablets.
Thermal analysis instruments must always be accurate, true and precise in order to deliver reproducible results within a given range. Performing a calibration determines whether your module is delivering correctly measured values or whether it needs an adjustment. The different parameters that must be calibrated are temperature, heat flow, mass, length and modulus. In this Webinar, we will discuss the basics of calibration and adjustment in thermal analysis whilst offering some useful tips and hints.Read more >
G-protein coupled receptors (GPCRs) are the primary target class of currently marketed drugs, accounting for around a third of all drug targets of approved medicines. However, almost all the screening efforts for novel ligand discovery rely exclusively on cellular systems overexpressing the receptors. Current receptor assay systems are based on measurement of either ligand displacement or downstream functional responses, rather than direct observation of ligand binding. Issues of allosteric modulation, probe dependence and functional selectivity create challenges in selecting suitable assays formats. Therefore a method that directly measures GPCR-ligand interactions, independent of binding site, probe and signalling pathway would be a useful primary and orthogonal screening method. An alternative ligand discovery strategy would be the direct measurement of GPCR-ligand interactions by label-free technologies, such as surface plasmon resonance (SPR). However label-free biophysical screening methods have not been routinely applied to membrane proteins. Current developments are looking at improving GPCR biosensor assays for SPR instruments and applying these to a range of drug discovery and biological functions, including kinetic analysis, allosteric discovery, fragment screening and functional selectivity. Biosensor-based direct screening methods enable the identification of the interaction of both orthosteric and allosteric ligands with solubilised, wild type GPCRs, in a label-free and cell-free environment, thus overcoming the limitations of indirect and displacement assay methods.Read more >
Drug target validation is a major obstacle to drug development leading to high rates of late-stage failure because the pivotal study in drug development - the randomised trial – occurs at the end of the development pipeline.
Genetic studies using the principle of Mendelian randomisation reproduce key elements of a randomised trial ensuring target validation can take place earlier in development.
A second major obstacle in drug development is the understanding of individual differences in drug efficacy and safety due to naturally occurring variation in gene encoding proteins involved in drug disposition – a key component of stratified medicines research.
The Illumina Drug Development Array is designed to address issues and enable genomic discoveries to be used in drug development.
The array combines the genome-wide tag SNP content of the Illumina Human Core BeadChip (240,000 highly-informative genome-wide tag SNPs and over 20,000 high-value markers) with a novel 200,000 custom marker set designed to support studies of drug target validation and treatment response. The array is relevant to full range of human drug targets and medical disorders.
The webinar will:
- Introduce the concept of Mendelian randomisation studies for target selection and validation in drug development
- Discuss the concept of the ‘druggability’ and the ‘druggable genome’
- Describe development of the content of the Illumina drug development array based on an updated set of genes encoding druggable targets and the proteins involved in in drug absorption, distribution, metabolism and excretion (ADME)
- Prof. Aroon Hingorani, Chair of Genetic Epidemiology, Institute of Cardiovascular Science, University College London
- Prof. John Overington, Visiting Professor of Computational Chemical Biology, Institute of Cardiovascular Science, University College London
- Dr. Anna Gaulton, Senior Data Integration and Development Officer – ChEMBL, European Bioinformatics Institute, Hinxton
Special Guest Terry Kenakin Ph.D. will be taking part in our LIVE Q&A session answering your questions!
[ABOUT THIS WEBINAR]
Ligand bias is a well-established concept in the GPCR research field that is beginning to emerge as a means to optimize GPCR targeted drug design. Most approved medications that target GPCRs act as either agonists or antagonists of heterotrimeric G protein and β-arrestin pathways. In many cases, this classical signaling paradigm leads to both efficacy and on-target adverse events. Biased GPCR ligands have the ability to activate or inhibit with greater selectivity one of the two downstream effector proteins and its subsequent signaling cascades. The goal of this webinar is to illustrate in vitro characterization of GPCR ligand bias and its translation to in vivo proof-of concept using TRV027, an AT1R modulator, as an exemplar biased ligand.
> What attendees will learn about?
• Review of GPCR signaling
• Introduction to concept of ligand bias and quantification thereof
• Utility of 2nd messenger assays in GPCR drug discovery
• Pre-clinical biased ligand proof-of-concept
Thermal Analysis is often used to investigate pharmaceutical substances. Polymorphism, pseudo-polymorphism, phase diagrams, stability, and purity determination can all be measured by thermal analysis.
The four main techniques of thermal analysis, DSC, TGA, TMA, and DMA are ideal for characterizing such substances. The chief advantage is that properties can be measured as a function of the temperature or time over a wide temperature range, from –150 to 1600 °C.
In this Webinar, we will show how thermal analysis is used to investigate pharmaceutical substances. We will present some typical examples measured by DSC, TGA, TMA or DMA.
Presentation 1: Jason Causon, Senior Applications Specialist, Sciex
Development of bioanalytical LC-MS methods for the detection of therapeutic peptides and the proteolytic fragments of larger proteins and antibodies is growing along with the increasing number of peptide and protein drugs entering clinical research and development. Development of these methods present challenges that are different to small molecule method development because of the multiple charge states possible for a given peptide, the abundance of product ion possibilities and the large number of proteolytic fragments possible from a protein digest. In addition to optimizing for sensitivity, on-column HPLC method development is time consuming for the same reasons. In this webinar we present an automated tuning and optimization workflow with on-column validation using DiscoveryQuantTM 3.0 software with the new ChromaTune feature to overcome some of these challenges and make the optimization of peptide MRM methods easier and less time consuming.
Presentation 2: Remco van Soest, Product Manager, Sciex
Electrospray Ionization efficiency increases at lower flow rates. In this Webinar we will discuss how microLC can help you improve sensitivity in sample limited applications in bio-analysis by LC-MS. In order to analyse the same volume of sample as is typically injected in a conventional LC-MS system, up to 50 µL, we have developed a microLC system that allows for fast on-line pre-concentration on a short trap column. Because of the higher flow rates that can be used for loading the sample on the trap-column, sample throughput is not affected by using microLC flow rates for the LC-MS analysis.
In 2014 RNDC, the second largest wholesaler of alcoholic beverages in the US, built a suite of Sales Force Automation tools that would transform the way their field sales force went to market. Their focus was to drive sales success by increasing the sales rep’s effectiveness on each sales call, delivering higher customer satisfaction with the sales process and information.
RNDC's challenges were:
Provide best-in-class information technology that outpaces their competitors and creates a significant point of difference
Keep pace with emerging technologies
Build mobile solutions focused on Sales Force Automation
Standardize wherever possible and drive utilization
In this presentation, Bill Smith, Director of Sales Quality Assurance, will discuss how sales leadership and BI developers, working with MicroStrategy Mobile technology, developed best-in-class mobile applications, delivering real-time analytics to the field sales teams at RNDC.
Accelerating Pharma R&D with Novel MS Applications for High Throughput Screening (HTS), Drug Imaging and Integrating MS and NMR data for high confidence structure verification of small molecules.
This webinar will introduce novel MS and NMR solutions and its applications in pharmaceutical research:
> NMR Spectroscopy and Mass Spectrometry are two fundamental techniques for small molecule structure verification. Bruker FUSION-SV - a new software solution for comprehensive fully automated small molecule structure verification – simplifies and accelerates the drug design and discovery phases in the pharmaceutical industry significantly. The new Bruker FUSION-SV™ is a software solution integrating high resolution accurate mass (HRAM) data and complementary NMR data, into one result - increasing significantly the specificity and throughput for small organic molecule structure verification. Synthesis chemists will get a prompt result without being an expert spectroscopist.
> Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) instruments are ideally suited for high throughput screening (HTS) in drug discovery. Not only speed, simplicity and robustness are the convincing arguments for MALDI-TOF MS but the inherent strength of a label- and solvent-free technique. The webinar will explain the technique and advantages of MALDI-TOF MS and present automation solutions for highest throughput and speed (less than 1 second per sample).
> Finally the webinar will describe how the MALDI technology is used for small molecule imaging when coupled to modern 7 T (Tesla) FT-MS instrumentation. Drugs and metabolites can be visualized and distinguished one from the other directly measured from tissue samples. These results can be linked with histological information derived from the very same tissue, giving new insights into drug action and toxicity.
Near Infrared spectroscopy as a great PAT tool for pharmaceutical processes-from raw material ID, integrated process control and to final product testing.
This webinar will focus on benefits of using NIR spectroscopy in several pharmaceutical processes. Examples of NIR application for raw material ID, process control testing and final product will be given. Challenges in implementing NIR spectroscopy in the analytical process will be discussed.
Live/dead differentiation of microorganisms helps to ensure safe food production
This webinar introduces viability PCR as a fast and powerful tool to analyze food samples for the presence of potentially harmful microbes. Viability real-time PCR utilises the DNA-masking compound propidium monoazide (PMA). PMA enters dead and membrane-compromised pathogen cells and binds to DNA, making the DNA inaccessible to detection by PCR. Live/dead differentiation is important for procedures such as: hygiene testing (success of decontamination processes), water testing (distinguishing between live and dead legionella for regulatory compliance), and several other important applications.
Do you want to learn more? http://www.qiagen.com/gb/landing-pages/detected-dead-or-alive-the-blu-v-way
Given the emergence of wind energy as the most sustainable renewable energy alternative, there are immense growth opportunities for the companies supplying chemicals and materials for wind blades. This briefing will investigate the trends in the wind blade manufacturing industry and the implications on the chemicals and materials suppliers.
Why You Should Attend:
• Larn about the current unmet needs of wind blade manufacturers
• Identify the drivers and restraints for the chemical and material suppliers
• Identify the key chemistries and respective growth areas
Mergers and acquisitions (M&A) have been the most frequently used method by companies across geographies to grow and remain competitive in the market place.
In this briefing, we will discuss the M&A opportunities in China’s Industrial Valves Market from 3 main industries: Food and Beverage; Oil and Gas, and Chemical; Power Generation.