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    • Cell Culture Contamination Part 1 – Understanding Cell Culture Contamination
      Cell Culture Contamination Part 1 – Understanding Cell Culture Contamination Louie Tran Recorded: Jun 11 2013 4:00 pm UTC 46 mins
    • Recent studies have shown that at least 20% of the animal cell cultures currently in use in the US are contaminated by either microorganisms or other cell lines. This three part live, on-line seminar series will review the scope of this major problem and examine some of its causes and techniques for avoiding it. It will also explore some key, easy to employ strategies for preventing these losses by careful culture management.

      This webinar will discuss good aseptic technique: developing a practical approach to aseptic technique; reducing day-to-day contamination problems in the lab; and helpful hints for avoiding contamination.

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    • Understanding the How’s and Why’s of Cell Culture Contamination and Ways to Avoi
      Understanding the How’s and Why’s of Cell Culture Contamination and Ways to Avoi Mark Rothenberg Recorded: Oct 23 2012 4:00 pm UTC 59 mins
    • Contamination of cell cultures, whether from bacteria, fungus, virus or other cell line is of critical importance to laboratory personnel. Studies have shown that at least 20% of the animal cultures in existence today are contaminated. Cell line contamination can result in decreased productivity, loss of critical study tools, impact data quality and reduce bioprocessing capacity. In hopes of helping to reduce this common problem, this tutorial will focus on:
      • Understanding the nature of contamination and its consequences.
      • Understanding the major sources and causes of cell culture contamination.
      • Discussing aseptic technique and its use in reducing day-to-day contamination.
      • A discussion on the use of antibiotics and their potential hidden dangers.
      • Simple methods to monitor for contamination and the importance in the use of cryopreserved cell lines.

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    • Cell Culture Contamination Part 2 - Aseptic Technique
      Cell Culture Contamination Part 2 - Aseptic Technique Hannah Gitschier Recorded: Jul 17 2013 4:00 pm UTC 46 mins
    • Studies have shown that at least 20% of the animal cell cultures currently in existence are contaminated by either microorganisms or other cell lines. This three part live, on-line seminar series will review the scope of this major problem, examine some of its causes, and discuss techniques for avoiding contamination. It will also explore some key, simple strategies to monitor for contamination and prevent losses through careful culture management.

      This webinar will specifically focus on aseptic technique: developing a practical approach to aseptic technique; reducing day-to-day contamination problems in the lab; and helpful hints for avoiding contamination.

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    • Alternative And Rapid Microbiological Methods: Microbiology Of The 21st Century
      Alternative And Rapid Microbiological Methods: Microbiology Of The 21st Century Dr Benoit Ramond, Head of Microbiology & Sterile Technology, Sanofi Upcoming: Apr 8 2019 8:00 am UTC 75 mins
    • Today Pharmaceutical industry remains conservative for microbiology testing methods and has reluctance to develop and to use Alternative and Rapid Microbiological Methods (RMM) supported by a number of misunderstandings and prejudgments based on the following myths:
      - RMM are not accepted by regulation authorities,
      - RMM will never replace classical microbial methods,
      - RMM will not offer return on investment (ROI),
      - Data generated from RMMs will exceed current specifications and limits involving increase in batch rejections.

      Nevertheless a movement is in progress for the use of new technologies and systems because classical microbial methods, in spite of their long return of experiences and their confidence for the regulatory point of view, have a number of disadvantages such as:

      - Time to results in days to weeks,
      - Results vary with microbial population, media, culture conditions,
      - Lack of reactivity in case of exceeding limit results,
      - Sensitivity could be insufficient giving underestimations in the contamination risk,
      - Existence of confluent growth.

      This webinar provides an overview of the current situation about RMM technologies, regulatory expectations, it proposes some initiatives facilitating the implementation of RMM including a strategy for validation and it gives a projection for the perspectives of the RMMs for the future.

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    • The Laboratory’s Role in the National Healthcare Safety Network
      The Laboratory’s Role in the National Healthcare Safety Network Robert L. Sautter, Ph.D., HCLD (ABB), CC Recorded: Apr 9 2018 6:00 pm UTC 58 mins
    • In this webinar, Dr. Sautter will discuss the important collaboration efforts between the government and healthcare facilities to stop prevalent and dangerous hospital-acquired infections. After the webinar, you will be able to:

      • Explain how the laboratory and the NHSN can work together to lower infection rates in hospitals
      • Learn how to lower rates of infections, such as blood culture contamination, MRSA and C. difficile
      • Identify how pre-analytic culture collection can affect the results of clean catch and catheter-related infections
      • Discuss how laboratories can work together with the NHSN, an infection surveillance program created by the CDC to eliminate HAIs, to identify problem areas and measure the progress of prevention initiatives

      P.A.C.E. credit* is available for your participation at http://qmark.beckmancoulter.com/r/325Safety.html

      Presenter: Dr. Sautter is a teacher, lecturer and industry consultant. He earned his B.S. and M.S. degrees from Eastern Michigan University in the areas of biology and molecular biology, respectively, and his Ph.D., from Wayne State University, in Detroit, Mich., in microbiology. During his career, he held positions as a medical technologist, director of microbiology and medical director for a number of laboratories, before becoming an esteemed consultant for a variety of industry leaders in the area of microbiology.

      *Beckman Coulter Inc. is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. These credits are recognized by the State of California. Most programs also provide State of Florida credits (with valid license number). At this time, we cannot issue continuing education credits for those who provide healthcare (or work for an institution that provides healthcare) in Massachusetts or Vermont.

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    • Update on public outreach for CCS projects
      Update on public outreach for CCS projects Toby Lockwood Recorded: Dec 14 2016 12:15 pm UTC 30 mins
    • Following a few early failures of large-scale carbon capture and storage (CCS) demonstration projects due to public opposition to the technology, a considered public communication strategy is now regarded as an essential factor in the success of any prospective CCS project. Most active opposition to CCS has occurred in parts of Europe, where public fears over CO2 leaks, water contamination, or ‘industrialisation’ of rural areas combined with opposition by environmental groups and others to fossil fuels playing any role in a future energy mix. However, many other projects have since won acceptance or even widespread support, thanks either to improved public engagement or more favourable local context. Several key features of a successful communication strategy have been identified, including the need for engagement early in the process, encouraging and responding to community feedback, building and maintaining trust in the project developers, and use of a dedicated communications team with clear messages which are tailored to their intended audience. This report provides a comprehensive review of the public outreach strategy and results at most notable CCS demonstrations to date, and looks to future challenges for CCS communication. With the barrier of local acceptance appearing surmountable in most regions, the problem of making the wider case for CCS as a viable option for climate change mitigation largely remains. This could potentially be addressed through education initiatives and more effective use of mass media.

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    • Authentication of Cell Lines for Pre-Clinical Cancer Research
      Authentication of Cell Lines for Pre-Clinical Cancer Research Yvonne A. Reid, Ph.D. Recorded: Jun 22 2015 4:00 pm UTC 58 mins
    • Join us on June 22nd for a special Corning-sponsored webinar presented by ATCC®.

      Abstract:
      Animal cell lines are important in vitro systems and tools for scientists in diverse disciplines such as basic cell biology, genetic mapping, gene expression and gene therapy. Cell line authentication and characterization are crucial in these activities, yet they are underappreciated by most research scientists. Over the years numerous cell lines have been shown to be misidentified due, in part, to poor techniques and inadequate verification of cell line authenticity. Technological advances have given rise to improved capabilities. Cell line authentication now requires a comprehensive strategy that employs several complementary technologies for systematic testing for morphology, microbial contaminations, cellular identity/cross-contamination as well as functionality. The validity of conclusions drawn from research data is dependent on consistent and unequivocal verification of cell line identity and function. It is estimated that the financial loss incurred by poorly characterized or misidentified cell lines is in the millions of dollars. An overview of the current technologies used to authenticate cell lines will be presented.

      Speaker Bio:
      Dr. Yvonne A. Reid joined ATCC in 1980 and during the mid-1980’s her research focused on the use of DNA hypervariable probes for the intraspecies identification of cell lines. The evolution of this work has led to the implementation of routine screening of all human cell lines by STR analysis. She co-chaired the ATCC SDO committee on the Development Consensus Standard on the Authentication of Human Cell Lines: Standardization of STR profiling. Dr. Reid has more than 30 years of experience in cell biology, immunology and molecular biology. As Collection Scientist for the Cell Biology Program for over 10 years, she was responsible for acquisition of new animal cell lines and hybridomas into the Cell Biology General Collection.

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    • Holistic solutions for mine tailings and water
      Holistic solutions for mine tailings and water Jason Palmer, Commercial Product Manager, Dewatering Recorded: Dec 22 2015 7:00 am UTC 34 mins
    • Almost all mines have waste streams from overburden through tailings to excess water and as the mine life develops these streams require storage or treatment. While some may have acid generation potential or heavy metals contamination much of the waste is inert and can be safely stored in stacks or dams that are stabilized and revegetated at the end of the mine life.

      Advances in technology are enabling changes to the way dams are managed, increasing the solid content of the tailings stream decreases the size of the storage, increases the water recovery, reducing risk and enabling simpler closure. Advances in filtration have made the stacking of tailings an alternative in arid regions or areas where a tailings dam may not be acceptable.

      The technical feasible solution with the lowest life of mine cost is typically influenced by the source material availability, geographic conditions, production rate and local legislations. Analyzing the available technologies to arrive at the best holistic solution requires a deep understanding of the available technologies combining process, geotechnical and strategic planning.

      This webinar introduces the technologies and services that Outotec has developed to respond to the evolving industry needs for safe and effective management of tailings and mine water.

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    • What’s in your Flask? Global Answers from Authentication Testing (NA)
      What’s in your Flask? Global Answers from Authentication Testing (NA) Amanda Capes-Davis, Chair Person - International Cell Line Authentication Committee (ICLAC) Recorded: Oct 6 2015 4:30 pm UTC 55 mins
    • Cell culture underpins research throughout the life sciences. Continuous cell lines have been used as culture models for many cell types, and assembled into panels for drug discovery and development. However, problems like cross-contamination are quite common and can render some cell lines unsuitable as research models. Authentic cells are typically overgrown by the contaminant over several passages to give a misidentified or false cell line.

      Misidentified cell lines can be detected through authentication testing. Short tandem repeat (STR) profiling was subsequently introduced as an international reference method, and a consensus standard for human cell line authentication published by the American National Standards Institute (ANSI). International agreement has allowed all laboratories to compare their cell line stocks, resulting in a new wave of misidentified cell lines being discovered.

      Funding bodies and journals are moving to set requirements for reporting of preclinical research. A good understanding of cell line provenance is also essential.

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    • What’s in your Flask? Global Answers from Authentication Testing (EMEA)
      What’s in your Flask? Global Answers from Authentication Testing (EMEA) Amanda Capes-Davis, Chair Person - International Cell Line Authentication Committee (ICLAC) Recorded: Oct 6 2015 1:00 pm UTC 51 mins
    • Cell culture underpins research throughout the life sciences. Continuous cell lines have been used as culture models for many cell types, and assembled into panels for drug discovery and development. However, problems like cross-contamination are quite common and can render some cell lines unsuitable as research models. Authentic cells are typically overgrown by the contaminant over several passages to give a misidentified or false cell line.

      Misidentified cell lines can be detected through authentication testing. Short tandem repeat (STR) profiling was subsequently introduced as an international reference method, and a consensus standard for human cell line authentication published by the American National Standards Institute (ANSI). International agreement has allowed all laboratories to compare their cell line stocks, resulting in a new wave of misidentified cell lines being discovered.

      Funding bodies and journals are moving to set requirements for reporting of preclinical research. A good understanding of cell line provenance is also essential.

      Read more >
    • Shale gas, public health and planning: five things to think about for shale gas
      Shale gas, public health and planning: five things to think about for shale gas Michael Stephenson, Director of Science and Technology, British Geological Survey, UK Recorded: Sep 22 2015 3:00 pm UTC 42 mins
    • According the US Energy Information Administration, shale gas will provide half of the United States’ domestic gas by 2035. Shale gas is also well developed in Canada and being developed in South America and China. The economic benefits of shale are likely to cause other countries to look at this energy source. But shale gas is extracted by hydraulic fracturing which frees the gas from the tight shale and is different in scale and technique from more traditional ways of extracting oil and gas. What can local people expect from these sorts of operations and what do local planners, environmental engineers and health professionals need to know?

      In this webinar, Mike Stephenson will consider five important issues: noise and visual impact, truck traffic, air quality, groundwater contamination and induced earthquakes. He will look at the reasons why they occur, the effects they have, and aspects of their regulation – all explained in simple non-technical language.

      Prof. Mike Stephenson is Chief Scientist at the British Geological Survey. He has advised the UK government on shale gas and carbon capture and storage issues, and spoken at parliamentary events including at the House of Lords Select Committee on Economic Affairs. He has also contributed to debates at the UK Royal Society and Royal Academy of Engineering, and the European Parliament.

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    • Sorting Out the Implications of U.S. EPA VI Guidance
      Sorting Out the Implications of U.S. EPA VI Guidance David Gillay, Barnes & Thornburg LLP, Dr. Blayne Hartman, Hartman Environmental Geosciences & Brad Willy, Terra Vapor Recorded: Aug 6 2013 6:00 pm UTC 76 mins
    • Change is in the air on the vapor intrusion front. Literally and figuratively. On April 16, the U.S. Environmental Protection Agency released a draft document, the OSWER Final Guidance For Assessing And Mitigating The Vapor Intrusion Pathway From Subsurface Sources To Indoor Air — External Review Draft for public comment. The release of EPA’s guidance comes just months before ASTM is poised to release a revised version of E 1527 that adds definitions of migrate/migration to address the vapor pathway as a potential conduit for contamination.

      As attention being placed on vapor risk increases, environmental professionals need to stay abreast of the changes and their implications. With the long-awaited federal guidance now out for public comment, environmental due diligence professionals, lenders, as well as prospective purchasers of properties like drycleaners, gas stations, and other types of properties impacted by petroleum or solvents have a valuable resource for understanding VI risk, assessing it and ultimately, managing it as appropriate for their own risk tolerance. Join us at this webinar to hear the perspectives of three experts on:

      • The implications of the federal vapor guidance and an insiders’ unique take on hot button issues;
      • How one environmental professional talks to his clients about vapor risk and protects their liability exposure; and
      • How vapor risk is being mitigated and managed in today’s deals.

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    • Emerging Risk: Heading off Regulatory Scrutiny on Residential Appraisals
      Emerging Risk: Heading off Regulatory Scrutiny on Residential Appraisals Jack Huntress, EDR, Liz Green, REL-E-VANT SOLUTIONS, Larry Schnapf, Schnapf LLC Recorded: Jul 17 2013 6:00 pm UTC 75 mins
    • For lenders operating in the shadow of the Dodd-Frank Act, CFPB and other regulatory enforcement agencies are focusing their efforts on consumer protection, disclosure and transparency and deem these critical to all areas of an institution’s compliance and operation. A dizzying array of new rules and regulations, often disruptive to existing operations, are raining down upon the mortgage lending industry. Now, however, it’s not enough to simply be aware of emerging rules and regulations. Little known requirements and regulations which have been on the books for years without being enforced are now getting renewed attention from those agencies, likely opening up an entirely new front in the uphill battle to stay compliant. One of the greatest potential risks to lenders arises from requirements for residential property appraisals and evaluations. It is likely we will see stricter environmental underwriting and more regulatory scrutiny on lenders’ risk management policies. Discover now where lenders are most at risk, and learn about cost-effective measures that can be taken to stay out of the regulatory crosshairs.

      The presenters will:

      • Identify existing rules and regulations, little-known and long unenforced, that are likely to be revitalized by regulatory enforcers;
      • Spell out the specific risks that residential property contamination, including vapor mitigation, will pose to a mortgage lender;
      • Explain how the gamut of new and existing requirements will impact traditional due diligence requirements; and
      • Predict the possible financial impact upon lenders, as well as offering potential solutions for risk mitigation.

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