EFFECT OF CELL CULTURE PROCESS CHANGE FROM FED-BATCH TO CONTINUOUS ON PRODUCTIVITY AND PRODUCT QUALITY
Integrated continuous bioprocessing has attracted a growing interest due to its potential to improve agility and flexibility in the manufacture of therapeutic proteins. To convert an existing fed-batch cell culture process to continuous, or perfusion, the major technical hurdles include maintaining steady state cell culture performance and generating product with comparable product quality attributes. In this presentation, we evaluated three molecules including a fusion protein, an aglycosylated monoclonal antibody (mAb), and a glycosylated mAb. Steady state culture at high cell density was achieved for all three molecules, which allows the delivery of products with consistent product quality and adequate productivity. However, as compared to fed-batch processes, product quality and cell specific productivity differences were observed in perfusion cultures. Further studies indicated that it was feasible to modulate product quality in perfusion process by adding process levers in culture medium. It was also feasible to increase cell specific productivity through medium and process optimization. This presentation provides an insight into the product quality and productivity differences between traditional fed-batch and perfusion cell culture processes and potential approaches to addressing these differences.
We all know that automation is critical to digital transformation. But what is the difference between BPM / DPA and RPA technologies? How do they fit together?
Join Bizagi, a leading provider of Digital Process Automation, and UiPath, the leading global enterprise Robotic Process Automation (RPA) company, for practical advice about how these technologies combine to help you enable enterprise-wide digital transformation.
Register now for important insights into:
o What automation really means for the future of your human workforce
o Why companies that have invested in RPA also need broader and deeper process orchestration
o How organizations using BPM / DPA technologies can unlock greater efficiencies by adding in RPA
The webinar will be hosted by Bizagi’s Nitish Pargal, Brandon Brown of UiPath and our guest speaker Craig Le Clair – VP and Principal Analyst at Forrester Research.
** This webinar is in German, with English subtitles **
BCB is a subsidiary of Postbank and is one of the biggest established service providers for payments and banking products in Germany. In 2017, BCB processed over 6.5 billion payments and has about 1500 full-time employees.
Cognitive Automation is seen by Postbank as one important lever to make banking operations more efficient, faster and scalable. During this episode of our Cafe series, we will discover Postbank's RPA journey that started early 2016 to now having 50 processes automated by leveraging 40 Blue Prism Digital Workers. Postbank is also looking in combining RPA with Cognitive and OCR capabilities to maximize the Automation level and achieve faster client response times.
Serkan Saracuz, Head of Organization & Processes shares Postbank's successful implementation process, lessons learned as well as examples and successes with Thomas Bepler of Blue Prism.
Key takeaways from this episode of the Blue Prism Café are:
> The pre-requisites for an RPA deployment
> How to ensure internal buy-in and adoption
> How RPA can improve client experience
> Real-world example of processes and lessons learned
Learn how machine learning is being used to optimize common business processes and the improvements that can be achieved. In this 45-minute webinar, you will see case studies of numerous machine learning applications that your organization may need.
WHO SHOULD ATTEND?
-IT professionals wanting to learn more about ML
-CTO - evaluating applying Machine Learning to core technology strategies
-CIO - support business units looking to apply Machine Learning
-Innovators within companies
-Mid-Small businesses looking for competitive advantage with Machine Learning
WHAT WILL YOU LEARN?
-Various case studies of how Machine Learning was applied to common business processes
-Methodology for evaluating if Machine Learning is a viable solution
-Learn the truth and myth of Machine Learning for common business processes
Malcolm Trigg, Solutions Consultant at Micro Focus, explains how Robotic Process Automation (RPA) products can access legacy mainframe ‘green screen’ applications and automate core business processes.
This 10 minute overview will give a bitesize look at the challenges, approaches and solutions available when using RPA, and Malcolm will be available to answer viewer questions after.
Watch a demonstration and learn how Bizagi can help you gain business insights by allowing users to easily abstract and consume process data across your operationsRead more >
Learn how Colombian Bank Bancolombia manage to drive efficiencies across their business.
Learn how using Live Processes can:
•Help improve day to day business operations.
•Build processes right from within your browser.
•Quickly implement new applications for any business need.
Watch a demonstration and learn how using Bizagi Live Processes can help improve day to day business operations, build processes right from within your browser. and quickly implement new applications for any business need.Read more >
Ageas is one of the largest providers of personal and commercial insurance in the U.K., and was no stranger to automation when it began using Blue Prism’s Digital Workforce in 2014. But from the very start, it knew it couldn’t achieve its process efficiency, waste reduction, and risk mitigation goals unless it built an internal culture in which everyone in the organization fully understood the benefits of Robotic Process Automation (RPA), and embraced all it could do for them, the company, and its customers.
In this episode of our Blue Prism Café, join the team behind Ageas’ leading change management practices, where their goals were to eliminate worries about the impact on employment,actively encourage their employees to welcome process automation, and create a culture in which the employees think of the robots as additional team mates that are responsible for doing mundane, repetitive back office tasks 24/7/365.
Key takeaways will include:
• Selling the benefits, and managing the message of RPA within the business
• Real-life examples on how to humanize the Digital Workforce
• Ensuring effective aftercare for implemented processes
• Delivering maximum automation benefits back to the business
DXC Technology is an end-to-end IT services and solutions company, helping clients harness the power of innovation to thrive on change. Through partnership with Blue Prism, DXC Technology has launched a new digital platform called DXC Agile Process Automation (APA) that combines the availability of the cloud and the power of robotic process automation. APA enables an organization’s business processes to become digital through cloud based, Robotics as a Service. Leveraging the latest cloud technologies, the Blue Prism robots can be scaled on-demand to meet the needs of businesses through a consumption-based model.
Join Stan Leong and Dar Suy with DXC Technology, along with Shail Khiyara of Blue Prism, to learn how the APA platform is enabling businesses to digitize key processes with Robotics as a Service.
Key takeaways from this episode of the Blue Prism Café will be:
Robotics as a Service is delivering REAL value.
> APA scales. Really.
> APA decreases change management costs. Realist solution.
> APA automates the right opportunities. Real time.
> APA moves your spend from fix to variable cost. Time to get real?
Digital transformation is one of the hottest topics of today, and it involves businesses, people, technologies, and methodologies. Join this webcast to discover how process automation—orchestration, robotic process automation, dynamic workflow, and machine learning—makes digital transformation a reality. By using adaptive technologies and unique methodologies, you can truly transform your operations and delight your customers.
Join us to hear from guest speaker Rob Koplowitz, VP and Principal Analyst at Forrester, and Genpact’s Cora SeQuence customer Apple Leisure Group’s Jason Metcalf, VP Operations and Business Transformation, who will share their story of digital process automation success.
For more details:http://www.genpact.com/lp/genpact-cora-sequence
Robotic process automation (RPA) is gaining the interest of many enterprises. It’s easy to see why; Enterprises everywhere are under immense pressure to digitize operations and they see a future where routine operations are fully automated. But how does RPA fit alongside BPM in a broader digital process automation strategy?
Join us to hear Forrester analyze the current state of the process automation market, examining RPA's relationship to artificial intelligence (AI) and business process management (BPM), before proposing a blueprint for an overall digital operating model.
Forrester's Craig Le Clair will provide insights from across leading digital process automation projects, including:
•A model for the interaction between RPA, AI and BPM
•How to overcome the challenges of governance, CoE and security
•How to facilitate the relationship between Business, Technology and BPM
Who should attend: Digital Technology Leaders, Application Development Leaders, IT and Business Process Professionals
Shop Direct is one of UK’s largest pure play online retailers with revenues over £1.86bn. Head of RPA and Business Agility, Lindsay Harrison has worked for the Shop Direct since 2006 and has been instrumental in pioneering RPA within the company.
For our second Blue Prism Café, Lindsay Harrison joins Shail Khiyara, Chief Marketing and Experience Officer at Blue Prism to discuss Shop Direct’s RPA journey.
Based on real-world insights and experiences, Lindsay will outline the tangible benefits of RPA technology by defining clear metrics. Metrics that include hours returned back to the business, priority scoring their processes, delivering increased revenue and scaling automation across the entire enterprise. By outlining what success looks like for any RPA deployment, webinar participants can build a roadmap for their own digital transformation.
Key takeaways from this webinar will include:
> What processes should be targeted first for RPA
> How do you measure RPA success, what are the metrics
> Finding the right RPA talent and “reskilling” employees
caling RPA is often a challenge in many organizations who are struggling with whether to focus on number of Digital Workers, hours returned back to the business, or other metrics. In addition, culture barriers are often challenging to overcome and can impact scale.
Ann Delmedico, Vice President, Intelligent Process Automation at Prudential Financial joined Shail Khiyara, Chief Customer Officer at Blue Prism to discuss the RPA journey at Prudential. For 140 years, Prudential Financial has helped individual and institutional customers grow and protect their wealth. The company is recognized as a trusted brand and one of the world’s most admired companies.
Based on real-world experiences Ann speaks about what is required to build and scale a successful digital workforce, including how to address culture barriers.
Key takeaways from this recording include:
> RPA drivers and measures of success
> Scaling means more than number on “bots”
> Shaping an outcome oriented RPA culture
The development and application of continuous manufacturing processes for vaccines presents both great opportunity as well as significant challenges, both technical and cultural, for the global industry. The key drivers are manufacturing capacity and flexibility, speed to market, and improved quality through the application of Quality-by-Design and Process Analytical Technology (QbD/PAT). Given the diversity of immunogens (toxoids, conjugate and subunit vaccines, live-attenuated and inactivated viruses, VLPs, etc.), and the variety of unique processes currently utilized to produce either single- or multi-component vaccines, it is unlikely that the transition to continuous processing will happen overnight. Additionally, cultural challenges are faced whenever a new mode of operation appears to some as “too different”, especially in a traditionally conservative sector like the developed-world vaccine industry. That said, market forces, global climate change, and Nature’s propensity to fill unoccupied niches with emerging infectious diseases will undoubtedly induce a first round of pioneers to explore this exciting new design space, ultimately leading to a more nimble industry and more and better opportunities for protection for the global population.Read more >
Digital technologies are fundamentally changing the way insurance claims are processed, with huge potential customer service and efficiency gains. But what needs to change for touchless claims to become a reality?Read more >
Live webinar with: CUNA Mutual Financial Group & New York Life in partnership with EXL
Insurance companies have an opportunity to leapfrog generations of technology advancements and are driving end to end transformation impacting customer experience through back-end processes such as claims-processing, underwriting and providing policy quotes. Today, more and more businesses have turned to Robotic Process Automation (RPA) and a Digital Workforce to help streamline their processes in order to remain competitive while being able to delight their customers thanks to fast turnaround times and accurate information.
In this "Insurance Industry" special episode of our Blue Prism Café, we will be welcoming guests from Credit Union National Associate (CUNA) and New York Life Insurance Company for a conversation around "why" and "how" to implement a Digital Workforce, and more importantly what best practices our guests can share to make RPA a long-term and scalable solution for your business, regardless of the industry.
Key takeaways will include:
• Specificities of the insurance industry for implementing RPA
• Real-life examples of implemented processes across various lines of businesses and their results
• Best practices and lessons learned from launching and scaling a Digital Workforce
• Brian Golden, Senior Manager Process Automation, CUNA Mutual Financial Group
• Daniela Caldararu, Director Intelligent Automation and Insight Services, CUNA Mutual Financial Group
• Eric Greenstein, Head of Strategic Portfolio Management & Process Automation, New York Life
• Ahson Pai, Global Head of Digital Consulting, EXL
• Xina Seaton, VP Customer Experience, Blue Prism
This live webinar will include a live-audience Q&A, so make sure to pre-register and join us on the 8th of January. If you cannot make it on the day, a recording will be made available online afterwards.
Discover how creating an agile culture enables you not only to deliver digital solutions fast, but also to make sure that they return results – including huge financial savings and complete project payback in 2 months or less
Join this webinar hosted by Bizagi Customer Travelport, a travel commerce platform connecting the world’s leading B2B travel providers with pioneering B2B payment solutions. We’ll discuss how agility has radically redefined the way Travelport operates by:
- Creating a culture of collaboration and experimentation
- Shining a light on the simplification of critical processes
- Delivering rapid results that demonstrate digital transformation
Who should attend: Digital Technology Leaders, Application Development Leaders, IT, Business and Process Professionals.
Learn how to use Bizagi to build highly personalised processes to meet your customer needs.
Watch now to learn how Bizagi can help you:
•Use data, content and context to enable organizations to quickly define smart and unique offerings.
•Easily define context for a product or service.
•Create highly personalised services with no coding needed.
See how easily you can collaborate with peers to model and then publish a new or existing process. Use the capability in Modeler Collaboration Services to share, review and edit models in the cloud before publishing and tracking stakeholder acknowledgment of new processes or changes existing models.Read more >
Join healthcare industry experts at Bizagi and Microsoft for an insightful webinar on enabling digital transformation in your organization. In Part II of this webinar series, learn key strategies to help you achieve success:
Practical tips and a roadmap on delivering critical digital healthcare processes
How to improve collaboration within your organization
How top healthcare organzations are increasing cost savings and improving efficiency
Intelligence is the rocket fuel to all Process Automation projects, whether the task is low-level (RPA) or high-level complex processes. In this session, you will hear a holistic but pragmatic approach to implementing intelligence as part of a company’s digital transformation journey.
Join this webinar to hear Frank Beyer and Bizagi as they discuss:
- How to structure your approach to RPA and to higher-level process automation
- Identifying processes that require a higher level of cognitive skills
- How to digitize cognitive work such as analysis, synthesis and evaluation
Who should attend: Digital Technology Leaders, Application Development Leaders, IT and Business Process Professionals
Process automation has tremendous promise in the HR arena to create efficiencies, improve the employee experience and job satisfaction. As we move forward, digital employees will perform transactional work, allowing our human employees to pivot and focus on the employee experience, which in turn improves the customer experience and bottom line. In this Blue Prism Café, Curt Burghardt, VP of HR Shared Services & HR Systems at Walgreens will share his insights with Shail Khiyara, CMXO from Blue Prism, on how RPA is being used to drive strategic improvements at Walgreens.
Key takeaways from this webinar will include:
> Why HR is fertile ground for RPA deployments
> Why IT governance, security and privacy are key criteria in selecting an RPA vendor
> Going from a POC to enterprise scale
> How to measure success on each process automated
> Championing consensus and change management
> Getting corporate buy and building a dedicated RPA team
Gal Horvitz, SVP Genpact Digital, and Founder and CEO at PNMsoft, a Genpact Company, discusses the challenges companies face when changing business processes. He outlines the solutions Genpact offers through design thinking, dynamic workflow solutions, and system integration, to bring about quicker and more effective change.Read more >
Going paperless not only helps with the environment but also saves time, money and improves security. WL Bank, a specialist for real estate financing, shares its journey of going paperless for critical decision making process.
David Schenke, Application Development Manager of WL Bank, will discuss:
•How process automation improves decision making
•How mobility empowers stakeholders to be agile and responsive
•How WL Bank is transforming to a paperless organization
Who should attend: Digital Technology Leaders, Application Development Leaders, IT and Business Process Professionals.