Advances in Mass Spectrometry for the Analysis and Bioanalysis of Antibody-Drug

Presented by

Arnaud Delobel, PhD

About this talk

ADCs are complex compounds resulting from the coupling of cytotoxic small molecules to a monoclonal antibody. Their characterization as well as their bioanalysis (quantification in biological fluids) remains challenging. Mass spectrometry at different levels (intact, middle, peptide) can be a valuable tool, and can now be used in a regulated environment thanks to advances in both hardware and software.

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