Achieving Seamless Scale-Up and Technology Transfer – A Case Study in Single-Use

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Presented by

Ying Wang, Ph.D., Senior Scientist I, Manufacturing Sciences at AbbVie Bioresearch Center

About this talk

Title: Achieving Seamless Scale-Up and Technology Transfer – A Case Study in Single-Use Bioreactors A systematic scale-up strategy is critical in enabling a rapid and robust technical transfer. For a program involving a CHO cell culture process, a combination of mass-transfer (kLa) studies, computational simulation and scale-down model experiments were used within this newly developed work-flow. Utilizing this approach, scale-up was successfully accelerated (

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