Molecular diagnostics in pediatric oncology

Presented by

Dr. Bastiaan Tops

About this talk

In this webinar, industry thought leader Dr. Bastiaan Tops will share his diagnostic laboratory's recent accomplishments in precision medicine at a national pediatric oncology center in the Netherlands. Dr. Tops will discuss the clinical value of Whole-Transcriptome Sequencing (WTS) and Whole-Exome Sequencing (WES) for improved diagnosis and treatment selection. Dr. Tops is Head of the Diagnostics Lab at Princess Maxima Center for pediatric oncology in Utrecht, Netherlands. Since 2018, the lab has introduced several new tests in routine diagnostics (e.g., WES and WTS), and has facilitated Whole-Genome Sequencing (WGS) in a research setting. In one of his recent publications on JCO Precision Oncology he demonstrated the “Improved Gene Fusion Detection in Childhood Cancer Diagnostics Using RNA Sequencing."
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This series is brought to you by Roche. We are committed to providing you with educational content, from key opinion leaders, related to personalized diagnostics. We aim to ensure on ongoing conversation is taking place in this evolving area of healthcare. Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. Twenty-nine medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology & Life Sciences Industry eight years in a row by the Dow Jones Sustainability Indices. The Roche Group, headquartered in Basel, Switzerland, is active in over 100 countries and in 2015 employed more than 91,700 people worldwide. In 2015, Roche invested CHF 9.3 billion in R&D and posted sales of CHF 48.1 billion. Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. For more information, please visit