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Understanding and Applying USP Method <1112>

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Brady Carter, Research Scientist, Decagon Devices, Inc.
Understanding and Applying USP Method <1112>: Application of Water Activity Determination to Nonsterile Pharmaceutical Products

This seminar will provide an overview of USP Method <1112> and how it can be used to save time and money. USP <1112> outlines strategies based on water activity that can reduce the amount of microbial limit testing needed for products with lower water activities. Microbial limit testing can be time consuming and expensive and reducing the amount of testing will result in savings. Products with water activity levels below the growth limits of pathogenic organisms are candidates for reduced microbial testing since the organisms cannot effectively grow under lower water activities. Utilization of this method requires an understanding of water activity and this seminar will define water activity and describe methods for accurately measuring it. The seminar also will discuss the relationship between water activity and microbial growth and discuss strategies for implementing USP <1112> to save time and money.

5 Major Learning Objectives:

What is water activity?
How are water activity and moisture content different?
How is water activity measured?
What is USP method <1112>?
How does USP method <1112> facilitate reduced microbial limit testing?
How can USP method <1112> save time and money?


Brady Carter, Research Scientist

Brady Carter, MS is a Research Scientist at Decagon Devices, Inc. Before joining Decagon, he was an Assistant Research Scientist at Washington State University. Mr. Carter received his bachelor degree in Botany from Weber State University in 1997 and his master’s degree in Cereal Chemistry from Washington State University in 1999.
Sep 15 2009
76 mins
Understanding and Applying USP Method <1112>

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  • Title: Understanding and Applying USP Method <1112>
  • Live at: Sep 15 2009 3:00 pm
  • Presented by: Brady Carter, Research Scientist, Decagon Devices, Inc.
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