Hot Melt Extrusion for Poorly Soluble Drugs

Presented by

Scott T. Martin, Thermo Fisher, Karl Kolter, BASF

About this talk

Hot Melt Extrusion (HME) is becoming an important technology within the Pharmaceutical Industry as a means for formulating poorly water-soluble active pharmaceutical ingredients (API’s). Additionally, HME provides greater drug bioavailability. This Webinar will cover: • A review of Hot Melt Extrusion Technology. • Modification to the traditional extrusion system for pharmaceutical needs. • An economically-feasible continuous process and solvent-free manufacture. • The role of polymers and plasticizers. • The use of low temperatures to minimize API degradation. • Optimization of HME Formulation and Process. Scott T. Martin, Senior Application Specialist, Thermo Fisher Scientific Dr. Karl Kolter, Ph.D., Head of Global R&D Project Management Excipients BASF SE, Germany, Pharma Ingredients and Services BASF reserves the right to limit access to this event.

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