Discover TumorGraft3D: A Technical Deep-Dive for Advancing Oncology Research

Presented by

Stefano Cairo, PhD, Senior Global Scientific Director, Champions Oncology

About this talk

Organoids are 3D in vitro models that recapitulate the structural and functional complexity of the healthy or diseased tissue of origin. The use of organoids represents a step forward in basic and applied research, as it supports and accelerates the investigation of fundamental mechanistic properties of human tissues, such as development, regeneration, and repair, and provides a groundbreaking tool to support drug discovery and personalized medicine by capturing patient specificity while recapitulating in vivo tissue organization and functions in vitro, overcoming conventional 2D cultures and animal models limitations. Champions Oncology has leveraged a biobank of 1,500+ TumorGraft patient-derived xenograft (PDX) models and 100+ patient primary samples to generate a versatile 3D platform to enhance drug discovery by coupling the assessment of patients’ heterogeneity with the time and cost-effectiveness of an in vitro assay. Join us for a webinar that provides a thorough analysis of Champions' revolutionary TumorGraft3D platform, an ex vivo multiclonal 3D organ-like tumor culture assay derived from our industry-leading clinically relevant patient-derived xenograft (PDX) models. Key Takeaways Attendees of this webinar will be able to: • Gain comprehensive insights into the TumorGraft3D platform and its robust capabilities • Discover specific readouts including cytotoxicity, flow cytometry, high-content imaging, DRUGseq, and luciferase-tagged models for superior research outcomes • Understand the applications of the platform to refine your preclinical programs
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Champions Oncology delivers innovative solutions to oncology drug development, accelerating the journey from the research bench to the clinic – decreasing timelines, lowering costs, and ultimately saving patient lives. Learn more about Champions Oncology's capabilities, our service platforms and educational topics affecting our industry on our Webinar Channel.