In this discussion, Dr. Asmeret Asefaw Berhe, Director of the Office of Science for the U.S. Department of Energy, details the impacts of an Exascale machine on the DoE’s research arsenal -- what it means for science, advancement, and increased access for people who make breakthroughs possible. Host Justin Hotard, HPE’s Executive Vice President and General Manager, HPC & AI, will share his vision of the possibilities when Exascale meets AI and takes on big data workloads.