Reconstructing the surface of the eye using stem cells

Presented by

Dr Sajjad Ahmad, MRCOphth, PhD, Academic Clinical Lecturer, NESCI

About this talk

Reconstructing the surface of the eye using stem cells: from lab to limbus The cornea is the clear front of the eye and is important for the transmission of light to the retina at the back of the eye for visual perception. World Health Organisation statistics show that approximately 5 million people worldwide suffer from blindness due to diseases of the cornea. The surface of the cornea is composed of an epithelium and this is maintained by stem cells located at the edge of the cornea, in a region known as the limbus. These so-called limbal stem cells can be lost, most commonly from chemical burns to the eye, resulting in the painful and blinding disease of limbal stem cell deficiency. In this presentation, I will discuss how basic adult and embryonic stem cell biology can be used to treat limbal stem cell deficiency by replacing the lost stem cells.

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