Advanced Models for 3D Cancer Applications

In recent years, three-dimensional (3D) cell culture models have been emerging as the preferred in vitro cancer model as they better mimic the in vivo tumor microenvironment. For instance, 3D cultures develop hypoxic cores and demonstrate gradients of soluble factors and a diffusion profile for drugs similar to solid tumors. Understanding the interactions between cancer cells and other cell types in the tumor microenvironment is also critical to predicting therapeutic efficacy. In this webinar, Audrey Bergeron will review: •An introduction to 3D cell culture •Assay techniques in spheroid microplates •Several 3D cancer models and technology tools used to better capture the complexity of the tumor microenvironment in assay-compatible formats. About the Presenter: Audrey Bergeron is an applications scientist for Corning Life Sciences. She evaluates new products and develops protocols and technical documents using Corning cell culture products. She also provides product training to Corning employees and customers, and assists technical services with customer support by helping to troubleshoot customer experiments.