Cell based assays; the guiding light for drug discovery

Drug Discovery research is highly competitive and time sensitive. Invitro cell based assays provide the first biological hurdle in the progression of potential new chemical entities in their progression to becoming a therapeutic drug; Majority of the synthesized compounds get filtered out in this step, hence its extremely important to set up the assays in such away that the outcome provide true reliable measure of effect of each compound. In webinar I will be speaking about • Introduction to invitro cell based assay development • Different level of assays • Critical biochemical parameters to look out for • Target Classes at present • Impact and Scope in Drug discovery • Case study and paper discussion Design, Synthesis of Novel, Potent, Selective, Orally Bio-available Adenosine A2A Receptor Antagonists and Their Biological Evaluation J. Med. Chem. 2017, 60, 2, 681–694 Publication Date: January 5, 2017 https://doi.org/10.1021/acs.jmedchem.6b01584