The skin and the nervous system are closely related; sensory neurons that innervate the skin are
in charge of sensing external changes (temperature, touch and itch), but they are also involved in
sensing internal stimulus and mediate immune responses. The functional regulation mediated by
sensory neurons is more evident in sensitive skin condition, thus, regulation of sensory neuron’s
activity plays a fundamental role in skin balance. Consequently, studying sensory neurons in
product design is a cutting-edge way to develop innovative skin care products.
AntalGenics is biotech company expert in the development of neurocosmetic ingredients. Here
we present our latests molecules: Calmapsin® and Capsisilence®.
Our neurocosmetic ingredient for sensitive skin, Calmapsin®, is a novel capsaicinoid molecule that
improves the biological properties of capsaicin. Calmapsin® is an innovative neurocosmetic
ingredient that calms itch, protects from oxidative stress, and improves skin barrier function.
Capsisilence® is a new neurocosmetic ingredient design to calm itchy scalp. Capsisilence® acts
on sensory neurons and immune cells diminishing itch and inflammation, leading to a reduction in
scalp redness, flaking and dandruff reappearance.